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PABPC3

Available structures

Human UniProt search: PDBe RCSB

List of PDB id codes
4IVE

Identifiers

Aliases

PABPC3, PABP3, PABPL3, tPABP, poly(A) binding protein cytoplasmic 3

External IDs

OMIM: 604680; HomoloGene: 118007; GeneCards: PABPC3; OMA:PABPC3 - orthologs

Gene location (Human)
👁 Chromosome 13 (human)
Chr.	Chromosome 13 (human)^[1]
👁 Chromosome 13 (human) 👁 Genomic location for PABPC3 👁 Genomic location for PABPC3
Band	13q12.13	Start	25,096,136 bp^[1]
Band	13q12.13	End	25,099,254 bp^[1]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

parotid gland

epithelium of nasopharynx

amniotic fluid

pancreatic ductal cell

seminal vesicula

pylorus

lactiferous duct

buccal mucosa cell

oral cavity

vulva

n/a

More reference expression data

BioGPS

👁 Image 👁 Image
More reference expression data

Gene ontology
Molecular function	poly(A) binding RNA binding nucleic acid binding mRNA 3'-UTR binding poly(U) RNA binding
Cellular component	cytoplasm extracellular exosome cytosol nucleus cytoplasmic stress granule ribonucleoprotein complex
Biological process	mRNA metabolic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


5042


n/a

Ensembl


ENSG00000151846


n/a

UniProt


Q9H361


n/a

RefSeq (mRNA)


NM_030979


n/a

RefSeq (protein)


NP_112241


n/a

Location (UCSC)

Chr 13: 25.1 – 25.1 Mb

n/a

PubMed search

^[2]

n/a

Wikidata

View/Edit Human

Polyadenylate-binding protein 3 is a protein that in humans is encoded by the PABPC3 gene.^[3]^[4]^[5] PABPC3 is a member of a larger family of poly(A)-binding proteins in the human genome.

References

[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000151846 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Morris CM, Bodger MP (Mar 1993). "Localization of the human poly(A)-binding protein gene (PAB1) to chromosomal regions 3q22-q25, 12q13-q14, and 13q12-q13 by in situ hybridization". Genomics. 15 (1): 209–11. doi:10.1006/geno.1993.1037. PMID 8432538.
^ Feral C, Mattei MG, Pawlak A, Guellaen G (Nov 1999). "Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes". Hum Genet. 105 (4): 347–53. doi:10.1007/s004399900148. PMC 1865476. PMID 10543404.
^ "Entrez Gene: PABPC3 poly(A) binding protein, cytoplasmic 3".

External links

[edit]

PDBe-KB provides an overview of all the structure information available in the PDB for Human Polyadenylate-binding protein 3 (PABPC3)

v t e PDB gallery
👁 1g9l: SOLUTION STRUCTURE OF THE PABC DOMAIN OF HUMAN POLY(A) BINDING PROTEIN 1g9l: SOLUTION STRUCTURE OF THE PABC DOMAIN OF HUMAN POLY(A) BINDING PROTEIN 👁 1jgn: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2 1jgn: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2 👁 1jh4: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip1 1jh4: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip1 👁 2d9p: Solution structure of RNA binding domain 4 in Polyadenylation binding protein 3 2d9p: Solution structure of RNA binding domain 4 in Polyadenylation binding protein 3

PDB gallery

👁 1g9l: SOLUTION STRUCTURE OF THE PABC DOMAIN OF HUMAN POLY(A) BINDING PROTEIN

1g9l: SOLUTION STRUCTURE OF THE PABC DOMAIN OF HUMAN POLY(A) BINDING PROTEIN
👁 1jgn: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2

1jgn: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2
👁 1jh4: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip1

1jh4: Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip1
👁 2d9p: Solution structure of RNA binding domain 4 in Polyadenylation binding protein 3

2d9p: Solution structure of RNA binding domain 4 in Polyadenylation binding protein 3

v t e RNA-binding proteins
Butyrate response factor 1 Fragile X mental retardation protein Rev hu paraneoplastic encephalomyelitis antigens mRNA cleavage and polyadenylation factors Cleavage and polyadenylation specificity factor Cleavage stimulation factor host factor 1 protein Aconitase ACO1 ACO2 nuclear factor 90 proteins ILF2 Poly(A)-binding protein PABPC1 PABPC4 polypyrimidine tract-binding protein ribonucleoprotein RNA cap-binding protein Cap binding complex EIF4E EIF4G1 SMN complex proteins SMN1 SMN2 DDX20

RNA-binding proteins

👁 Stub icon

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References

Further reading

External links