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Protein-coding gene in the species Homo sapiens
SEC24A
👁 Image
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2NUP, 2NUT, 3EGD, 3EGX

Identifiers
AliasesSEC24A, SEC24 homolog A, COPII coat complex component
External IDsOMIM: 607183; MGI: 1924621; HomoloGene: 70131; GeneCards: SEC24A; OMA:SEC24A - orthologs
Gene location (Human)
👁 Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Band5q31.1Start134,648,785 bp[1]
End134,727,909 bp[1]
Gene location (Mouse)
👁 Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Band11|11 B1.3Start51,583,091 bp[2]
End51,654,461 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • jejunal mucosa

  • mucosa of sigmoid colon

  • oocyte

  • cartilage tissue

  • parotid gland

  • oral cavity

  • secondary oocyte

  • Epithelium of choroid plexus

  • tail of epididymis

  • tibia
Top expressed in
  • epithelium of small intestine

  • seminal vesicula

  • left lobe of liver

  • migratory enteric neural crest cell

  • salivary gland

  • lacrimal gland

  • submandibular gland

  • body of femur

  • lobe of prostate

  • cumulus cell
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10802

77371

Ensembl

ENSG00000113615

ENSMUSG00000036391

UniProt

O95486

Q3U2P1

RefSeq (mRNA)

NM_001252231
NM_021982

NM_001290785
NM_175255

RefSeq (protein)

NP_001239160
NP_068817

NP_001277714
NP_780464

Location (UCSC)Chr 5: 134.65 – 134.73 MbChr 11: 51.58 – 51.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SEC24 family, member A (S. cerevisiae) is a protein that in humans is encoded by the SEC24A gene.[5] The protein belongs to a protein family that are homologous to yeast Sec24.[6] It is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum.[5]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113615Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036391Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "SEC24 family, member A (S. cerevisiae)". Retrieved 2011-12-05.
  6. ^ Tang BL, Kausalya J, Low DY, Lock ML, Hong W (May 1999). "A family of mammalian proteins homologous to yeast Sec24p". Biochemical and Biophysical Research Communications. 258 (3): 679–84. Bibcode:1999BBRC..258..679T. doi:10.1006/bbrc.1999.0574. PMID 10329445.

Further reading

[edit]

External links

[edit]
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Protein transport protein Sec24A