I agree with jamesjiao - maybe directly dependant on cytoskeletal dysfunction would be better?
Since the original poster hasn't yet replied, it's unclear what he wants to say exactly.
I can see two possibilities:
a) ... numerous human diseases, of which cytoskeletal dysfunction was one.
b) ... numerous human diseases, all of which involve cytoskeletal dysfunction (as a condition/symptom rather than the name of a disease).
I vote for the latter, in which case I would suggest cotados8 to use words like 'involve' or 'be related to'. Having diseases
depend on a symptom just doesn't work with me. Correction:
The studies were also important to better understand numerous human diseases directly involving cytoskeletal dysfunction, e.g. Alzheimer's disease.
Logically speaking, now that there are numerous human diseases involved, "i.e." is no longer correct.