questioning

"Can you tell me what is your problem?" - Is this correct grammaticallay?

"Can you tell me what is your problem is?"

- this is gramatically correct but I'm not sure that I would ever actually say that.

I would say "What is your problem?", "Can you just tell me what your problem is?", "Can't you tell me what your problem is?"

If I was discussing it with a friend, I would say more delicately, "Can you tell me what the problem is?"