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Hi there π
This is the GitHub organization of the Hasenauer Lab at University of Bonn, Germany.
For our research in computational biology, we developed a number of tools, mostly around simulation of dynamical models and parameter inference.
The highlights are:
- pypesto for parameter estimation in Python
- PEtab for specifying parameter estimation problems in systems biology in an efficient and interoperable manner
- AMICI for scalable simulation and sensitivity analysis (Python / C++)
- pyABC for distributed and scalable ABC-SMC (Approximate Bayesian Computation - Sequential Monte Carlo) for parameter estimation of complex stochastic models (Python)
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distributed, likelihood-free inference
Python
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45
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python Parameter EStimation TOolbox
Python
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47
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Parameter estimation for dynamical models using high-performance computing, batch and mini-batch optimizers, and dynamic load balancing.
C++
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4
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PESTO: Parameter EStimation TOolbox, Bioinformatics, btx676, 2017.
MATLAB
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12
Repositories
Showing 10 of 30 repositories
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pyPESTO
Public
python Parameter EStimation TOolbox
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cOmicsArt
Public
This is the code to run cOmicsArt! Want to use it without installation - check out the website:
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JavaScript
0
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6
Updated
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pyABC
Public
distributed, likelihood-free inference
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pyscat
Public
Scatter search optimization in Python
Python
2
BSD-3-Clause
1
11
1
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Tutorial_BCML_2026
Public
This repository contains the tutorial for AMICI, PEtab and pyPESTO presented in the 2nd Bonn Conference on Mathematical Life Sciences.
Jupyter Notebook
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.github
Public
Organization profile
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C-COMPASS
Public
A Neural Network Tool for Multi-Omic Classification of Cell Compartments
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Extrinsic-apoptosis-Conversion-reaction-model
Public
This is the reproducible code for the manuscript titled "Nonlinear Mixed-Effect Models and Tailored Parameterization Schemes Enable Integration of Single-Cell and Bulk Data," which covers both the extrinsic apoptosis and conversion reaction models.
MATLAB
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MIT
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