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More comprehensive and more predictive models have the potential to advance biology, bioengineering, and medicine. Building more predictive models will likely require the collaborative efforts of many investigators. This requires teams to be able to share and reuse model components and modeling tools. Despite extensive efforts to develop standards such as the COMBINE/OMEX archive format, the Kinetic Simulation Algorithm Ontology (KiSAO), the Systems Biology Markup Language (SBML), and the Simulation Experiment Description Markup Language (SED-ML) and repositories such as BioModels and the Physiome Model Repository, it is still often difficult to share, reuse, and combine models and modeling tools. One challenge to sharing and reusing models is the disparate formats, model repositories, and simulation tools for different types of models. The proliferation of numerous similar formats, repositories, and tools makes it difficult, especially for non-experts, to find models and to find an appropriate simulation tool for each model. In addition, the existing model repositories have limited capabilities for sharing associated resources such as training data, simulation experiments, and visualizations. BioSimulators addressses these challenges by making it easier for researchers to share and reuse modeling tools.
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Registry of containerized biosimulation tools that support a standard command-line interface
Python
15
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Tutorials for BioSimulators
Jupyter Notebook
2
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Utilities for building standardized command-line interfaces for biosimulation software packages
Python
4
6
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Template for a repository for building a BioSimulators-compliant command-line interface and Dockerfile for a biosimulation program
Python
4
3
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Tool for validating that biosimulation software tools implement the BioSimulators standards for simulators
Python
7
2
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Summary of the technical documentation for BioSimulators
Python
Repositories
Showing 10 of 44 repositories
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Biosimulators_AMICI
Public
AMICI biochemical network simulation program via BioSimulators-compliant command-line interface and Docker container
Python
3
MIT
1
5
0
Updated
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Biosimulators
Public
Registry of containerized biosimulation tools that support a standard command-line interface
Python
15
MIT
0
16
7
Updated
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SimpleProcessBigraphRuntime
Public
A simple project demonstrating how to take a process bigraph input file, and run simulations / workflows utilizing a simple registry
Python
0
MIT
0
0
5
Updated
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Biosimulators_COPASI
Public
COPASI biochemical network simulation program via BioSimulators-compliant command-line interface and Docker container
Python
2
MIT
3
6
4
Updated
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Biosimulators_smoldyn
Public
Smoldyn biochemical network stochastic simulation program via BioSimulators-compliant python interface.
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bsew
Public
Wrapper package from running Process Bigraph experiments in a docker environment
Python
0
Apache-2.0
0
0
0
Updated
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bspil-basico
Public
BioSimulators Process Interface Library for COPASI through the Basico python wrapper
Python
0
Apache-2.0
0
0
0
Updated
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bscose
Public
Prototype Builder Library for Prototype of Sed2
Python
0
Apache-2.0
0
0
0
Updated
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bsander
Public
Analyzes a Process-Bigraph `.pbif` file, and creates a configuration that will run in a given environment.
Python
0
Apache-2.0
0
0
0
Updated
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compose-server
Public
This repo is intended to replace both the bio-check and bio-compose-server repos. The aforementioned repos will be archived.
Python
0
Apache-2.0
0
0
1
Updated
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