Novel Interventions to Improve Survival in Preterm Neonates

This Collection focuses on a topic central to every neonatologist’s practice: highlighting recent advances, interventions, and protocols that improve intact survival among neonates born at less than 37 weeks’ gestational age. Because these infants require highly specialized care, management strategies used for more mature neonates often cannot be directly applied. This Collection aims to showcase how care differs for this vulnerable population and to emphasize the innovations that are reshaping preterm neonatal management.

A particular emphasis is placed on management strategies and scalable care models suitable for low-resource settings. The Collection will critically examine current practices in neonatal intensive care units across diverse global contexts and explore the reforms needed to optimize outcomes for preterm infants. The emerging role of artificial intelligence in guiding the management of these neonates will also be addressed.

Neonatal mortality represents a substantial proportion of under-five mortality worldwide, with prematurity as a leading contributor. Accordingly, this issue will highlight not only postnatal treatment strategies, but also antenatal preventive approaches aimed at reducing the incidence of prematurity and improving the likelihood of neurologically intact survival when preterm birth does occur.

By integrating these various strategies and focusing on both preventive and therapeutic intervention points, this issue seeks to provide a comprehensive overview of current practices, advancements, and future research opportunities in the care of this high‑risk subgroup of neonates.

This Collection supports and amplifies research related to SDG 3: Good Health and Well-Being.

All submissions in this Collection undergo the journal’s standard peer review process, and all manuscripts authored by a Guest Editor(s) are handled by the Editor-in-Chief. As an open access publication, this journal levies an article processing fee (details here). We recognize that many key stakeholders may not have access to such resources and are committed to supporting participation in this issue wherever resources are a barrier. For more information about what support may be available, please visit OA funding and support, or email OAfundingpolicy@springernature.com or the Editor-in-Chief.