The Translational Cancer Biology section aims to provide a platform for the communication and dissemination of advances in cancer biology and their translational applications. It welcomes studies that explore the mechanisms underlying cellular transformation, tumor progression, and metastasis, as well as the biology of cancer stem cells and their immunological characteristics, with a focus on implications for translational applications. Particular emphasis is placed on investigations into epithelial-to-mesenchymal transition (EMT), tumor dormancy, and their interplay with immune system functions. This includes the dynamic interactions between tumor cells and various immune cell populations, and the diverse strategies tumor cells employ to evade immune surveillance, such as immune checkpoint expression, antigen loss, and immunosuppressive microenvironment modulation.
This section also highlights research focused on translational approaches and the development of innovative therapeutic strategies targeting these processes, including studies aimed at modeling to predict the efficiency of novel approach to targeting the above mechanisms.