Pathogenesis

Latest research

1. Shiga toxin-centered pathophysiology defines the therapeutic limits of enterohemorrhagic Escherichia coli infection

   • Ui-Seok Seo
   • Jun-Young Park
   • Chang-Ung Kim

   in Archives of Microbiology

   Article 16 June 2026

2. Hospital-treated infection associated with Alzheimer’s disease pathology: underlying mechanisms

   • Tatiana Barichello
   • Giselli Scaini
   • Felipe Dal-Pizzol

   in Molecular Psychiatry

   Article Open access 15 June 2026

3. Pyoderma gangrenosum caused by the molecular uncoupling of OTULIN catalytic activity and LUBAC binding

   • Barathram Swaminathan
   • Hwi M. Gil
   • Janet G. Markle

   in Nature Immunology

   Article Open access 15 June 2026

4. Host–virus determinants of Ebola virus persistence in a human cerebral organoid model

   • Lina Widerspick
   • Santiago Vidal Freire
   • César Muñoz-Fontela

   in Nature Microbiology

   Article Open access 12 June 2026

5. Pneumonia-driven ARDS: systemic injury, biological subphenotypes, and therapeutic implications

   • Raffaele Merola
   • Viola Lomonaco
   • Patricia Rieken Macedo Rocco

   in Critical Care: Sepsis and Severe Infection

   Article Open access 12 June 2026

6. Whipple’s endocarditis and biologic response modifiers: a case-based review of an intricate host-pathogen interaction

   • Lorenzo Bertolino
   • Raffaella Gallo
   • Emanuele Durante-Mangoni

   in Infection

   Article Open access 03 June 2026

7. NETosis associates with human TB lung tissue destruction and disease pathogenesis

   • Kimone L Fisher
   • Thabo Mpotje
   • Mohlopheni J Marakalala

   in EMBO Molecular Medicine

   Article Open access 02 June 2026

8. Dissecting myocardial and systemic drivers of cardiac dysfunction in the murine CVB3 myocarditis model using microRNA-guided viral detargeting

   • Sarah Ochs
   • Sandra Pinkert
   • Antje Beling

   in Basic Research in Cardiology

   Article Open access 29 May 2026

9. Osteomyelitis

   • Sandra R. Arnold
   • Vincenzo Giordano
   • James E. Cassat

   in Nature Reviews Disease Primers

   Article 28 May 2026

10. Microbial Resilience

    Book 2026

11. The vicious cycle from inflammation to pyroptosis: the core role of macrophage polarization imbalance in the pathogenesis of knee osteoarthritis

    • Xin Du
    • Feng Li
    • Li Peng

    in Molecular Biology Reports

    Article 21 May 2026

12. Reply to: A case definition with microscopy would help establish Vibrio as a cause of sea star wasting disease

    • Melanie B. Prentice
    • Grace A. Crandall
    • Alyssa-Lois M. Gehman

    in Nature Ecology & Evolution

    Article 19 May 2026

13. A case definition with microscopy would help establish Vibrio as a cause of sea star wasting disease

    • Thierry M. Work
    • Salvatore Frasca Jr.
    • Elise E. B. LaDouceur

    in Nature Ecology & Evolution

    Article 19 May 2026

14. Integrated analysis of transcriptome and proteome reveal that PDCoV infection induces autophagy-dependent ferroptosis to facilitate viral replication

    • Xiaozhu Yang
    • Xingyu Mi
    • Bo Yang

    in Veterinary Research

    Article Open access 18 May 2026

15. The alkylation of AIM2 by itaconate mediates macrophage PANoptosis during sepsis

    • Jiamin Ma
    • Ying Chen
    • Jinbao Li

    in Cellular & Molecular Immunology

    Article Open access 12 May 2026

16. Ferroptosis, orchestrated by GPX4 downregulation, serves as a critical mediator of neutrophil extracellular trap-driven pathology in hypoxic pulmonary edema

    • Yanli Sun
    • Xiaolong Shu
    • Fei Guo

    in Apoptosis

    Article 11 May 2026

17. Lactylation-regulated ferroptosis: mechanisms, disease associations, and therapeutic strategies

    • Yun Lei
    • Si-Qi Ding
    • Dong-Qiu Dai

    in Archives of Pharmacal Research

    Article 10 May 2026

18. Evaluation of the potential virulence of Mycobacterium avium subspecies paratuberculosis isolates from cattle in Uganda

    • Judah Ssekitoleko
    • Franziska Tanneberger
    • Julius Boniface Okuni

    in Brazilian Journal of Microbiology

    Article Open access 06 May 2026

19. The Pathophysiology of Spontaneous Preterm Birth: Emerging Mechanisms Reviewed by the Preterm Birth International Collaborative

    • Emmeli Mikkelsen
    • Emmanuel Amabebe
    • Michael J. Taggart

    in Reproductive Sciences

    Article Open access 06 May 2026

20. A molecular switch: antitoxin HigA integrates transcriptional activation by XreR and proteolytic clearance by Lon to balance virulence and stress adaptation in the fish pathogen Edwardsiella piscicida

    • Yin Gou
    • Jingjing Sui
    • Yonghua Hu

    in Marine Life Science & Technology

    Article 04 May 2026

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