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URL: https://omim.org/clinicalSynopsis/211980


#211980
Table of Contents

LUNG CANCER


INHERITANCE
- Somatic mutation [SNOMEDCT: 124975008] [UMLS: C1866227, C0544886 HPO: HP:0001442] [HPO: HP:0001442]
- Autosomal dominant [SNOMEDCT: 771269000, 263681008] [UMLS: C0443147, C1867440 HPO: HP:0000006] [HPO: HP:0000006]
RESPIRATORY
Lung
- Alveolar cell carcinoma [SNOMEDCT: 112677002, 36310008] [UMLS: C0007120 HPO: HP:0006519] [HPO: HP:0006519]
- Nonsmall cell lung cancer [SNOMEDCT: 254637007] [UMLS: C0007131 HPO: HP:0030358]
- Adenocarcinoma of lung [SNOMEDCT: 254626006] [UMLS: C0152013 HPO: HP:0030078]
NEOPLASIA
- Alveolar cell carcinoma [SNOMEDCT: 112677002, 36310008] [UMLS: C0007120 HPO: HP:0006519] [HPO: HP:0006519]
- Nonsmall cell lung cancer [SNOMEDCT: 254637007] [UMLS: C0007131 HPO: HP:0030358]
- Adenocarcinoma of lung [SNOMEDCT: 254626006] [UMLS: C0152013 HPO: HP:0030078]
MISCELLANEOUS
- Genes associated with susceptibility to lung cancer, e.g., FASLG (134638.0002), FAS (134637.0021), CHRNA5 (118505.0001), CHRNA3 (118503.0001)
- Genes associated with a protection against lung cancer, e.g., CASP8 (601763.0004), CYP2A6 (122720.0002)
- Mutations in EGFR (131550) are associated with altered response to treatment with tyrosine kinase inhibitors
MOLECULAR BASIS
- Susceptibility conferred by mutation in the epidermal growth factor receptor gene (EGFR, 131550.0006)

Creation Date:
John F. Jackson : 6/15/1995
joanna : 02/11/2019
joanna : 02/11/2019
joanna : 05/25/2016
alopez : 9/21/2004
mimadm : 6/15/1995

# 211980

LUNG CANCER


SNOMEDCT: 363358000;   ICD10CM: C34.90;   DO: 1324;   MONDO: 0008903;  


INHERITANCE
- Somatic mutation [SNOMEDCT: 124975008] [UMLS: C1866227, C0544886 HPO: HP:0001442] [HPO: HP:0001442]
- Autosomal dominant [SNOMEDCT: 771269000, 263681008] [UMLS: C0443147, C1867440 HPO: HP:0000006] [HPO: HP:0000006]
RESPIRATORY
Lung
- Alveolar cell carcinoma [SNOMEDCT: 112677002, 36310008] [UMLS: C0007120 HPO: HP:0006519] [HPO: HP:0006519]
- Nonsmall cell lung cancer [SNOMEDCT: 254637007] [UMLS: C0007131 HPO: HP:0030358]
- Adenocarcinoma of lung [SNOMEDCT: 254626006] [UMLS: C0152013 HPO: HP:0030078]
NEOPLASIA
- Alveolar cell carcinoma [SNOMEDCT: 112677002, 36310008] [UMLS: C0007120 HPO: HP:0006519] [HPO: HP:0006519]
- Nonsmall cell lung cancer [SNOMEDCT: 254637007] [UMLS: C0007131 HPO: HP:0030358]
- Adenocarcinoma of lung [SNOMEDCT: 254626006] [UMLS: C0152013 HPO: HP:0030078]
MISCELLANEOUS
- Genes associated with susceptibility to lung cancer, e.g., FASLG (134638.0002), FAS (134637.0021), CHRNA5 (118505.0001), CHRNA3 (118503.0001)
- Genes associated with a protection against lung cancer, e.g., CASP8 (601763.0004), CYP2A6 (122720.0002)
- Mutations in EGFR (131550) are associated with altered response to treatment with tyrosine kinase inhibitors
MOLECULAR BASIS
- Susceptibility conferred by mutation in the epidermal growth factor receptor gene (EGFR, 131550.0006)

Creation Date:
John F. Jackson : 6/15/1995

Edit History:
joanna : 02/11/2019
joanna : 02/11/2019
joanna : 05/25/2016
alopez : 9/21/2004
mimadm : 6/15/1995



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2026 Johns Hopkins University.
NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2026 Johns Hopkins University.
Printed: April 4, 2026