VOOZH about

URL: https://pubmed.ncbi.nlm.nih.gov/33006087/

⇱ The lingering manifestations of COVID-19 during and after convalescence: update on long-term pulmonary consequences of coronavirus disease 2019 (COVID-19) - PubMed


Clipboard, Search History, and several other advanced features are temporarily unavailable.
Skip to main page content
👁 Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

👁 Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Abstract

The long-term sequelae of coronavirus disease 2019 (COVID-19) are still unknown. Lessons from past viral epidemics reveal that, after recovery, patients with viral pulmonary infections can suffer from irreversible pulmonary dysfunction and demonstrate residual imaging or functional abnormalities. Residual ground glass opacities, consolidations, reticular and linear opacities, residual crazy paving pattern, melted sugar sign, and parenchymal fibrotic bands are several features found in the late or remission stages of COVID-19. These radiologic findings have been observed weeks after symptom onset, even after hospital discharge, and they may or may not correlate with clinical manifestations. High-resolution CT may be indicated to establish new baselines and track changes in residual impairments. In our previous review, we observed significant pulmonary sequelae in some COVID-19 survivors at follow-up. In this update, we review the current literature on the clinical and radiologic manifestations of post-recovery COVID-19 toward the end of hospital admission and after discharge.

Keywords: COVID-19; Co-morbidities; High-resolution CT; Recovery; SARS-CoV-2; Surveillance.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

👁 Fig. 1
Fig. 1
A 64-year-old woman presented with myalgia and low-grade fever to the emergency department. Baseline CT examination showed multifocal patchy ground glass opacities and interlobular septal thickening (a, b). The diagnosis of COVID-19 was confirmed later by RT-PCR. Follow-up imaging 35 days after initial CT demonstrated residual pure ground glass opacity without focal pleural thickening (c, d)
👁 Fig. 2
Fig. 2
A 44-year-old man with shortness of breath, cough and fever was referred to us for non-contrast chest CT. Multifocal bilateral peripheral ground glass opacities were identified (a, b), consistent with COVID-19. He returned for follow-up imaging 34 days after the initial presentation. Follow-up non-contrast chest CT demonstrates residual pulmonary opacities and fibrotic bands involving peripheral bilateral lung bases (ce)

References

    1. Chakraborty C, Sharma AR, Sharma G, et al. SARS-CoV-2 causing pneumonia-associated respiratory disorder (COVID-19): diagnostic and proposed therapeutic options. Eur Rev Med Pharmacol Sci. 2020;24(7):4016–4026. doi: 10.26355/eurrev_202004_20871. - DOI - PubMed
    1. Chen J, Qi T, Liu L, et al. Clinical progression of patients with COVID-19 in Shanghai, China. J Infect. 2020;80(5):e1–e6. doi: 10.1016/j.jinf.2020.03.004. - DOI - PMC - PubMed
    1. Yuan M, Yin W, Tao Z, et al. Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China. PLoS One. 2020;15(3):e0230548. doi: 10.1371/journal.pone.0230548. - DOI - PMC - PubMed
    1. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395(10223):507–513. doi: 10.1016/S0140-6736(20)30211-7. - DOI - PMC - PubMed
    1. Salehi S, Abedi A, Balakrishnan S, Gholamrezanezhad A. Coronavirus disease 2019 (COVID-19, 2019-nCoV): a systematic review of imaging findings in 919 patients. AJR Am J Roentgenol. 2020 doi: 10.2214/AJR.20.23034. - DOI - PubMed
Cite

NCBI Literature Resources

MeSH PMC Bookshelf Disclaimer

The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.