2018
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Severe capillary leak syndrome with cardiac arrest triggered by influenza virus infection
Abstract: Systemic capillary leak syndrome (SCLS), also known as Clarkson syndrome, is a rare disease with potential fatal outcome. The clinical picture involves leakage of fluid and protein from the bloodstream into peripheral tissues, resulting in hypoalbuminaemia, elevated haematocrit, oedema and hypotension. The spectrum of the symptoms ranges from discrete swelling/oedema of extremities to fulminant cardiogenic shock. We present a case with a 52-year-old man diagnosed with SCLS after being resuscitated from cardiac… Show more
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“…SCLS accompanying influenza, as observed in our case, is rare, and few cases have been reported [ 5 ]. SCLS leads to anasarca, which was reported for the first time by Clarkson et al [ 6 ] with a triad of signs, including concentrated blood due to the loss of plasma to tissue stroma, hypoalbuminemia, and hypotension.…”
Section: Discussionmentioning
confidence: 68%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…SCLS accompanying influenza, as observed in our case, is rare, and few cases have been reported [ 5 ]. SCLS leads to anasarca, which was reported for the first time by Clarkson et al [ 6 ] with a triad of signs, including concentrated blood due to the loss of plasma to tissue stroma, hypoalbuminemia, and hypotension.…”
Section: Discussionmentioning
confidence: 68%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“……”
Section: Discussionmentioning
confidence: 72%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“… 3 , 17 – 19 Influenza A is perhaps the most common viral ISCLS trigger, yet less than a handful of cases have been reported. 20 – 22 To the best of our knowledge this is the first report of influenza B precipitating an ISCLS attack. The exact mechanisms remain ill-defined; however, it is suggested that T-cell activation in response to influenza and other viruses increases the production of pro-inflammatory cytokines and complement activating proteins, which, coupled to an MGUS paraprotein induce immunopathological damage of the endothelial barrier.…”
Section: Discussionmentioning
confidence: 86%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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