2021
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COVID-19 associated Kawasaki-like multisystem inflammatory disease in an adult
Abstract: Recent reports have described a secondary Multisystem Inflammatory Syndrome in Children (MIS-C) after a prior COVID-19 infection that often has features of Kawasaki disease (KD). Here, we report the case of a 36-year-old woman who presented to the emergency department hypotensive and tachycardic after 1 week of fevers, abdominal pain, vomiting and diarrhea, and was found to have the classic phenotype of complete Kawasaki's Disease including nonexudative conjunctivitis, cracked lips, edema of the hands and feet… Show more
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“…D-dimer levels and D-dimer positivity were significantly higher in the present study. Patients with MIS-C have also been reported to have high ALT levels [28]. We did not find any differences between groups in terms of serum ALT levels or positivity.…”
Section: Discussioncontrasting
confidence: 62%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…D-dimer levels and D-dimer positivity were significantly higher in the present study. Patients with MIS-C have also been reported to have high ALT levels [28]. We did not find any differences between groups in terms of serum ALT levels or positivity.…”
Section: Discussioncontrasting
confidence: 62%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…This report 9 is an important addition to descriptions of MIS-A. 4,6,7,11,12 Other published case reports and case series of suspected MIS-A have described case presentations similar to those reported by Hékimian et al 9 Markedly elevated laboratory markers of coagulopathy and inflammation and evidence of cardiac dysfunction are typical, and can also be observed in severe acute COVID-19. Although the clinical presentation in some patients with severe COVID-19 could overlap with MIS-A, the pathophysiology may be different; distinguishing between the two syndromes has implications for treatment and long-term follow-up.…”
mentioning
confidence: 51%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Although this syndrome is more common in children, this case, along with several other reports of post–COVID-19 inflammatory syndrome in adults, shows that emergency physicians should consider this disease in their differential diagnoses for adults with prolonged fever, rash, conjunctivitis, lymphadenopathy, gastrointestinal symptoms, or headache in the setting of possible COVID-19 exposure or infection ( 4 , 7 ).…”
Section: Discussionmentioning
confidence: 62%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD).
Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD.
The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC).
Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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