Can DeepSeek R1 Distill 32B run on AMD Instinct MI300X 192GB?

YES — Runs Great

A72Great

○Estimated from fit model

DeepSeek R1 Distill 32B needs ~43.5 GB VRAM. AMD Instinct MI300X 192GB has 192.0 GB. With Q4_K_M quantization, expect ~229 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 43.5 GB, 228.7 tok/s, Runs well

43.5 GB required192.0 GB available

23% VRAM used

Fit status

Runs well

Decode

228.7 tok/s

TTFT

846 ms

Safe context

33K

Memory

43.5 GB / 192.0 GB

Memory breakdown

Weights19.5 GB

KV Cache3.9 GB

Runtime0.9 GB

Headroom19.2 GB

See how fast it feels

See how fast it feelsDeepSeek R1 Distill 32B on AMD Instinct MI300X 192GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step.

Given information:
 - Speed = 60 mph (miles per hour)
 - Time = 2.5 hours

Formula: Distance = Speed x Time

Calculation:
 Distance = 60 mph x 2.5 h
 = 150 miles

The train travels 150 miles.

Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time.

Breakdown:
 - First half: 1.25 hours at 60 mph = 75 miles
 - Stop: 20 minutes (no distance)
 - Second half: 1.25 hours at 60 mph = 75 miles

Total distance: 150 miles (same)
Total time: 2.5 h + 0.33 h = 2.83 hours
Average speed: 150 / 2.83 = 53 mph

The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 228.7 tok/s decode · 846ms TTFT (warm) · 572 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	A	Runs well	228.7 tok/s	462 ms	33K
Coding	A	Runs well	228.7 tok/s	846 ms	33K
Agentic Coding	A	Runs well	228.7 tok/s	1231 ms	33K
Reasoning	A	Runs well	228.7 tok/s	1000 ms	33K
RAG	A	Runs well	228.7 tok/s	1539 ms	33K

Quantization options

How DeepSeek R1 Distill 32B (32B params) fits at each quantization level on AMD Instinct MI300X 192GB (192.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	12.5 GB	Low	B62
Q3_K_S	3	15.7 GB	Low	B63
NVFP4	4	17.9 GB	Medium	B63
Q4_K_M	4	19.5 GB	Medium	B63
Q5_K_M	5	23.0 GB	High	B63
Q6_K	6	26.2 GB	High	B64
Q8_0	8	34.2 GB	Very High	B64
F16Best for your GPU	16	65.6 GB	Maximum	B68

Get started

Copy-paste commands to run DeepSeek R1 Distill 32B on your machine.

Run

ollama run deepseek-r1:32b

Your hardware

More models your AMD Instinct MI300X 192GB can run

Model	Params	Grade	Decode
👁 Mistral Devstral 2 123B Instruct	123B	S	59.9 tok/s
👁 Alibaba Qwen 3.5 122B A10B	122B	S	166.2 tok/s
👁 DeepSeek DeepSeek V4 Flash	284B	S	89.1 tok/s
👁 Alibaba Qwen 3.6 35B A3B	35B	S	525.4 tok/s
👁 Alibaba Qwen 3.5 35B A3B	35B	S	571.3 tok/s

Frequently asked questions

See all results for AMD Instinct MI300X 192GB See all hardware for DeepSeek R1 Distill 32B

URL: https://willitrunai.com/can-run/deepseek-r1-distill-32b-on-instinct-mi300x-192gb

⇱ DeepSeek R1 Distill 32B on AMD Instinct MI300X 192GB? YES