Can Gemma 4 E4B run on RX 6600 8GB?

YES — With Offload

A76Great

○Estimated from fit model

Gemma 4 E4B needs ~7.9 GB VRAM. RX 6600 8GB has 8.0 GB. With Q4_K_M quantization, expect ~18 tok/s.

Runtime: llama.cppCapacity: OffloadBandwidth: Very lowStack: StandardBottleneck: Memory bandwidth

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 7.9 GB, 18.3 tok/s, Runs with offload

7.9 GB required8.0 GB available

99% VRAM used

Fit status

Runs with offload

Decode

18.3 tok/s

TTFT

10565 ms

Safe context

18K

Memory

7.9 GB / 8.0 GB

Memory breakdown

Weights4.9 GB

KV Cache1.3 GB

Runtime0.9 GB

Headroom0.8 GB

See how fast it feels

See how fast it feelsGemma 4 E4B on RX 6600 8GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
 if len(arr) <= 1:
 return arr
 pivot = arr[len(arr) // 2]
 left = [x for x in arr if x < pivot]
 middle = [x for x in arr if x == pivot]
 right = [x for x in arr if x > pivot]
 return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
 """Sort a list using the quicksort algorithm.

 Args:
 arr: List of integers to sort.

 Returns:
 A new sorted list.
 """
 if len(arr) <= 1:
 return arr
 pivot = arr[len(arr) // 2]
 left = [x for x in arr if x < pivot]
 middle = [x for x in arr if x == pivot]
 right = [x for x in arr if x > pivot]
 return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 18.3 tok/s decode · 10.6s TTFT (warm) · 46 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

Very little memory headroom

You can run the model, but there is not much room left for longer context, bigger batches, extra apps, or future model updates.

Best improvement path

Buy headroom, not only minimum fit

A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	A	Tight fit	18.3 tok/s	5763 ms	18K
Coding	A	Runs with offload	18.3 tok/s	10565 ms	18K
Agentic Coding	B	Very compromised (needs ~0.6 GB host RAM)	10.4 tok/s	27145 ms	18K
Reasoning	A	Runs with offload	18.3 tok/s	12486 ms	18K
RAG	B	Very compromised (needs ~0.6 GB host RAM)	10.4 tok/s	33931 ms	18K

Quantization options

How Gemma 4 E4B (8B params) fits at each quantization level on RX 6600 8GB (8.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	3.1 GB	Low	A81
Q3_K_S	3	3.9 GB	Low	A81
NVFP4	4	4.5 GB	Medium	A80
Q4_K_MBest for your GPU	4	4.9 GB	Medium	A80
Q5_K_M	5	5.8 GB	High	F0
Q6_K	6	6.6 GB	High	F0
Q8_0	8	8.6 GB	Very High	F0
F16	16	16.4 GB	Maximum	F0

Get started

Copy-paste commands to run Gemma 4 E4B on your machine.

Run

ollama run gemma4:e4b

Your hardware

More models your RX 6600 8GB can run

Model	Params	Grade	Decode	Capabilities
👁 Alibaba Qwen 3.5 9B	9B	A	11.5 tok/s
👁 Tsinghua/Zhipu CodeGeeX 4 9B	9B	A	21.9 tok/s

Frequently asked questions

See all results for RX 6600 8GB See all hardware for Gemma 4 E4B

URL: https://willitrunai.com/can-run/gemma-4-e4b-on-rx-6600-8gb