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URL: https://willitrunai.com/can-run/hf-maziyarpanahi--gemma-3-12b-it-gguf-on-quadro-rtx-8000-48gb

⇱ gemma 3 12b it on Quadro RTX 8000 48GB? YES


Can gemma 3 12b it run on Quadro RTX 8000 48GB?

YES — Runs Great

C47Usable
Estimated from fit model

gemma 3 12b it needs ~14.7 GB VRAM. Quadro RTX 8000 48GB has 48.0 GB. With Q4_K_M quantization, expect ~63 tok/s.

Runtime: OllamaCapacity: RoomyBandwidth: MediumStack: BasicBottleneck: Balanced
Share:

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 14.7 GB, 63.3 tok/s, Runs well
14.7 GB required48.0 GB available
31% VRAM used

Fit status

Runs well

Decode

63.3 tok/s

TTFT

3056 ms

Safe context

395K

Memory

14.7 GB / 48.0 GB

Memory breakdown

Weights7.3 GB
KV Cache1.4 GB
Runtime1.2 GB
Headroom4.8 GB

See how fast it feels

See how fast it feelsgemma 3 12b it on Quadro RTX 8000 48GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API. When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed. Key benefits of running locally: - Full privacy: your prompts never leave your machine - No per-token cost or rate limits - Works offline once the model is downloaded - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb: Model size Q4 (4-bit) Q8 (8-bit) FP16 7B params ~4.3 GB ~7.5 GB ~14 GB 13B params ~7.9 GB ~13.9 GB ~26 GB 70B params ~42.7 GB ~74.9 GB ~140 GB Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 63.3 tok/s decode · 3.1s TTFT (warm) · 158 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

Older PCIe generation

PCIe 3.0 is workable, but it compounds the penalty when you offload heavily or try to scale across multiple cards.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatCRuns well63.3 tok/s1667 ms395K
CodingCRuns well63.3 tok/s3056 ms395K
Agentic CodingCRuns well63.3 tok/s4446 ms395K
ReasoningCRuns well63.3 tok/s3612 ms395K
RAGCRuns well63.3 tok/s5557 ms395K

Quantization options

How gemma 3 12b it (12B params) fits at each quantization level on Quadro RTX 8000 48GB (48.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
4.7 GB
LowC42
Q3_K_S
3
5.9 GB
LowC42
NVFP4
4
6.7 GB
MediumC42
Q4_K_M
4
7.3 GB
MediumC42
Q5_K_M
5
8.6 GB
HighC43
Q6_K
6
9.8 GB
HighC43
Q8_0
8
12.8 GB
Very HighC44
F16Best for your GPU
16
24.6 GB
MaximumC48

Get started

Copy-paste commands to run gemma 3 12b it on your machine.

Run

lms load hf-maziyarpanahi--gemma-3-12b-it-gguf && lms server start

Upgrade options

Hardware that runs gemma 3 12b it well

Mac Studio M3 Ultra 96GBBudget pick
96 GB Unified (+48)819 GB/s (+147)
C
Adds memory headroom for longer context windows and future model growth.76.1 tok/s decode

Adds memory headroom for longer context windows and future model growth.

~$3,999 MSRP

AMD Instinct MI210 64GBBest value
64 GB VRAM (+16)1638 GB/s (+966)
C
Raises estimated decode speed by about 140%.152.2 tok/s decode

Raises estimated decode speed by about 140%.

Adds memory headroom for longer context windows and future model growth.

~$10,000 MSRP

Frequently asked questions

See all results for Quadro RTX 8000 48GBSee all hardware for gemma 3 12b it