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⇱ InternLM 7B on AMD Instinct MI250X 128GB? YES


Can InternLM 7B run on AMD Instinct MI250X 128GB?

YES — Runs Great

B67Good
Estimated from fit model

InternLM 7B needs ~25.8 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~98 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
Share:

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 25.8 GB, 98.0 tok/s, Runs well
25.8 GB required128.0 GB available
20% VRAM used

Fit status

Runs well

Decode

98.0 tok/s

TTFT

1976 ms

Safe context

8K

Memory

25.8 GB / 128.0 GB

Memory breakdown

Weights4.3 GB
KV Cache7.8 GB
Runtime0.9 GB
Headroom12.8 GB

See how fast it feels

See how fast it feelsInternLM 7B on AMD Instinct MI250X 128GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 98.0 tok/s decode · 2.0s TTFT (warm) · 245 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatBRuns well98.0 tok/s1078 ms8K
CodingBRuns well98.0 tok/s1976 ms8K
Agentic CodingBRuns well98.0 tok/s2873 ms8K
ReasoningBRuns well98.0 tok/s2335 ms8K
RAGBRuns well98.0 tok/s3592 ms8K

Quantization options

How InternLM 7B (7B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
2.7 GB
LowB59
Q3_K_S
3
3.4 GB
LowB59
NVFP4
4
3.9 GB
MediumB59
Q4_K_M
4
4.3 GB
MediumB59
Q5_K_M
5
5.0 GB
HighB59
Q6_K
6
5.7 GB
HighB59
Q8_0
8
7.5 GB
Very HighB59
F16Best for your GPU
16
14.3 GB
MaximumB59

Get started

Copy-paste commands to run InternLM 7B on your machine.

Run

docker run --rm -it ghcr.io/ggerganov/llama.cpp:full \ --hf-repo "InternLM/InternLM-7B" \ --hf-file "InternLM-7B-Q4_K_M.gguf" \ -c 4096 -ngl 99

Upgrade options

Hardware that runs InternLM 7B well

Mac Studio M3 Ultra 256GBBudget pick
256 GB Unified (+128)
B
Adds memory headroom for longer context windows and future model growth.98 tok/s decode

Adds memory headroom for longer context windows and future model growth.

~$6,999 MSRP

Frequently asked questions

See all results for AMD Instinct MI250X 128GBSee all hardware for InternLM 7B