Can Leanstral 119B A6B run on AMD Instinct MI325X 256GB?

YES — Runs Great

S87Excellent

○Estimated from fit model

Leanstral 119B A6B needs ~109.4 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~133 tok/s.

Runtime: vLLMCapacity: RoomyBandwidth: HighStack: OptimizedBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 109.4 GB, 133.4 tok/s, Runs well

109.4 GB required256.0 GB available

43% VRAM used

Fit status

Runs well

Decode

133.4 tok/s

TTFT

1451 ms

Safe context

256K

Memory

109.4 GB / 256.0 GB

Memory breakdown

Weights72.6 GB

KV Cache8.8 GB

Runtime2.4 GB

Headroom25.6 GB

See how fast it feels

See how fast it feelsLeanstral 119B A6B on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
 if len(arr) <= 1:
 return arr
 pivot = arr[len(arr) // 2]
 left = [x for x in arr if x < pivot]
 middle = [x for x in arr if x == pivot]
 right = [x for x in arr if x > pivot]
 return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
 """Sort a list using the quicksort algorithm.

 Args:
 arr: List of integers to sort.

 Returns:
 A new sorted list.
 """
 if len(arr) <= 1:
 return arr
 pivot = arr[len(arr) // 2]
 left = [x for x in arr if x < pivot]
 middle = [x for x in arr if x == pivot]
 right = [x for x in arr if x > pivot]
 return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 133.4 tok/s decode · 1.5s TTFT (warm) · 334 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	S	Runs well	133.4 tok/s	791 ms	256K
Coding	S	Runs well	133.4 tok/s	1451 ms	256K
Agentic Coding	S	Runs well	133.4 tok/s	2111 ms	256K
Reasoning	S	Runs well	133.4 tok/s	1715 ms	256K
RAG	S	Runs well	133.4 tok/s	2638 ms	256K

Quantization options

How Leanstral 119B A6B (119B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	46.4 GB	Low	A75
Q3_K_S	3	58.3 GB	Low	A76
NVFP4	4	66.6 GB	Medium	A77
Q4_K_M	4	72.6 GB	Medium	A78
Q5_K_M	5	85.7 GB	High	A79
Q6_K	6	97.6 GB	High	A80
Q8_0Best for your GPU	8	127.3 GB	Very High	A82
F16	16	244.0 GB	Maximum	F0

Get started

Copy-paste commands to run Leanstral 119B A6B on your machine.

Run

docker run --rm -it ghcr.io/ggerganov/llama.cpp:full \
 --hf-repo "mistralai/Leanstral-2603" \
 --hf-file "Leanstral-2603-Q4_K_M.gguf" \
 -c 4096 -ngl 99

Your hardware

More models your AMD Instinct MI325X 256GB can run

Model	Params	Grade	Decode
👁 Mistral Devstral 2 123B Instruct	123B	S	50.8 tok/s
👁 Alibaba Qwen 3.5 122B A10B	122B	S	133.8 tok/s
👁 DeepSeek DeepSeek V4 Flash	284B	S	71.7 tok/s
👁 Mistral AI Pixtral Large 124B	124B	S	50.4 tok/s
👁 Alibaba Qwen 3 235B A22B	235B	S	67.7 tok/s

Frequently asked questions

See all results for AMD Instinct MI325X 256GB See all hardware for Leanstral 119B A6B

URL: https://willitrunai.com/can-run/leanstral-119b-a6b-on-instinct-mi325x-256gb

⇱ Leanstral 119B A6B on AMD Instinct MI325X 256GB? YES