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URL: https://willitrunai.com/can-run/llama-3.1-405b-on-b200-180gb


Can Llama 3.1 405B run on NVIDIA B200 180GB?

YES — With Q2_K

A84Great
Estimated from fit model

Llama 3.1 405B needs ~184.5 GB VRAM. NVIDIA B200 180GB has 180.0 GB. With Q2_K quantization, expect ~32 tok/s.

Runtime: llama.cppCapacity: OffloadBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Llama 3.1 405B at Q4_K_M needs 273.6 GB — too much for NVIDIA B200 180GB (180.0 GB). Runs at Q2_K (184.5 GB) with low quality.
Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 273.6 GB, exceeds 180.0 GB available
273.6 GB required180.0 GB available
152% VRAM needed

93.6 GB over capacity — needs offload or smaller quantization

Fit status

Too heavy

Decode

12.7 tok/s

TTFT

15228 ms

Safe context

4K

Memory

273.6 GB / 180.0 GB

Offload

30%

Memory breakdown

Weights247.1 GB
KV Cache7.7 GB
Runtime0.9 GB
Headroom18.0 GB

See how fast it feels

With memory offload — actual speed may be lower
See how fast it feelsLlama 3.1 405B on NVIDIA B200 180GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort: def quicksort(arr): if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) # Example usage numbers = [3, 6, 8, 10, 1, 2, 1] print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10] The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]: """Sort a list using the quicksort algorithm. Args: arr: List of integers to sort. Returns: A new sorted list. """ if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 12.7 tok/s decode · 15.2s TTFT (warm) · 32 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

Very little memory headroom

You can run the model, but there is not much room left for longer context, bigger batches, extra apps, or future model updates.

Best improvement path

Buy headroom, not only minimum fit

A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatFToo heavy13.0 tok/s8114 ms4K
CodingFToo heavy12.7 tok/s15228 ms4K
Agentic CodingFToo heavy12.1 tok/s23186 ms4K
ReasoningFToo heavy12.7 tok/s17996 ms4K
RAGFToo heavy12.1 tok/s28982 ms4K

Quantization options

How Llama 3.1 405B (405B params) fits at each quantization level on NVIDIA B200 180GB (180.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
158.0 GB
LowF0
Q3_K_S
3
198.5 GB
LowF0
NVFP4
4

Get started

Copy-paste commands to run Llama 3.1 405B on your machine.

Run

ollama run llama3.1:405b

Upgrade options

Hardware that runs Llama 3.1 405B well

AMD Instinct MI350X 288GBBudget pick
288 GB VRAM (+108)
A
Makes the model fit on the accelerator instead of staying completely out of reach.25.9 tok/s decode

Makes the model fit on the accelerator instead of staying completely out of reach.

Removes host-memory offload, which is usually the single biggest latency and throughput win.

~$8,000 MSRP

AMD Instinct MI325X 256GBBest value
256 GB VRAM (+76)
A
Makes the model fit on the accelerator instead of staying completely out of reach.11.9 tok/s decode

Makes the model fit on the accelerator instead of staying completely out of reach.

Adds memory headroom for longer context windows and future model growth.

~$20,000 MSRP

Frequently asked questions

See all results for NVIDIA B200 180GBSee all hardware for Llama 3.1 405B
226.8 GB
Medium
F0
Q4_K_M
4
247.1 GB
MediumF0
Q5_K_M
5
291.6 GB
HighF0
Q6_K
6
332.1 GB
HighF0
Q8_0
8
433.4 GB
Very HighF0
F16
16
830.2 GB
MaximumF0

Buy headroom, not only minimum fit. A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.