Can Mistral Nemo 12B run on RTX 6000 Ada 48GB?

YES — Runs Great

B61Good

○Estimated from fit model

Mistral Nemo 12B needs ~15.8 GB VRAM. RTX 6000 Ada 48GB has 48.0 GB. With Q4_K_M quantization, expect ~116 tok/s.

Runtime: OllamaCapacity: RoomyBandwidth: HighStack: BasicBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 15.8 GB, 115.6 tok/s, Runs well

15.8 GB required48.0 GB available

33% VRAM used

Fit status

Runs well

Decode

115.6 tok/s

TTFT

1675 ms

Safe context

128K

Memory

15.8 GB / 48.0 GB

Memory breakdown

Weights7.3 GB

KV Cache2.4 GB

Runtime1.2 GB

Headroom4.8 GB

See how fast it feels

See how fast it feelsMistral Nemo 12B on RTX 6000 Ada 48GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
 - Full privacy: your prompts never leave your machine
 - No per-token cost or rate limits
 - Works offline once the model is downloaded
 - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

 Model size Q4 (4-bit) Q8 (8-bit) FP16
 7B params ~4.3 GB ~7.5 GB ~14 GB
 13B params ~7.9 GB ~13.9 GB ~26 GB
 70B params ~42.7 GB ~74.9 GB ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 115.6 tok/s decode · 1.7s TTFT (warm) · 289 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	B	Runs well	115.6 tok/s	913 ms	128K
Coding	B	Runs well	115.6 tok/s	1675 ms	128K
Agentic Coding	B	Runs well	115.6 tok/s	2436 ms	128K
Reasoning	B	Runs well	115.6 tok/s	1979 ms	128K
RAG	B	Runs well	115.6 tok/s	3045 ms	128K

Quantization options

How Mistral Nemo 12B (12B params) fits at each quantization level on RTX 6000 Ada 48GB (48.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	4.7 GB	Low	C54
Q3_K_S	3	5.9 GB	Low	C54
NVFP4	4	6.7 GB	Medium	C54
Q4_K_M	4	7.3 GB	Medium	C54
Q5_K_M	5	8.6 GB	High	C55
Q6_K	6	9.8 GB	High	B55
Q8_0	8	12.8 GB	Very High	B56
F16Best for your GPU	16	24.6 GB	Maximum	B60

Get started

Copy-paste commands to run Mistral Nemo 12B on your machine.

Run

ollama run mistral-nemo

Frequently asked questions

See all results for RTX 6000 Ada 48GB See all hardware for Mistral Nemo 12B

URL: https://willitrunai.com/can-run/mistral-nemo-12b-on-rtx-6000-ada-48gb

⇱ Mistral Nemo 12B on RTX 6000 Ada 48GB? YES