Can Mixtral 8x7B run on MacBook Pro M4 Pro 64GB?

YES — Tight Fit

B64Good

○Estimated from fit model

Mixtral 8x7B needs ~38.4 GB VRAM. MacBook Pro M4 Pro 64GB has 46.1 GB. With Q4_K_M quantization, expect ~15 tok/s.

Runtime: llama.cppCapacity: TightBandwidth: LowStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 38.4 GB, 15.1 tok/s, Tight fit

38.4 GB required46.1 GB available

83% VRAM used

Fit status

Tight fit

Decode

15.1 tok/s

TTFT

12804 ms

Safe context

33K

Memory

38.4 GB / 46.1 GB

Memory breakdown

Weights28.7 GB

KV Cache2.0 GB

Runtime0.9 GB

Headroom6.9 GB

See how fast it feels

See how fast it feelsMixtral 8x7B on MacBook Pro M4 Pro 64GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step.

Given information:
 - Speed = 60 mph (miles per hour)
 - Time = 2.5 hours

Formula: Distance = Speed x Time

Calculation:
 Distance = 60 mph x 2.5 h
 = 150 miles

The train travels 150 miles.

Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time.

Breakdown:
 - First half: 1.25 hours at 60 mph = 75 miles
 - Stop: 20 minutes (no distance)
 - Second half: 1.25 hours at 60 mph = 75 miles

Total distance: 150 miles (same)
Total time: 2.5 h + 0.33 h = 2.83 hours
Average speed: 150 / 2.83 = 53 mph

The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 15.1 tok/s decode · 12.8s TTFT (warm) · 38 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

Shared-memory contention still exists

The OS, browser, and inference runtime all compete for the same physical memory pool, so real-world headroom is less forgiving than raw capacity suggests.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	B	Runs well	15.1 tok/s	6984 ms	33K
Coding	B	Tight fit	15.1 tok/s	12804 ms	33K
Agentic Coding	B	Tight fit	15.1 tok/s	18624 ms	33K
Reasoning	B	Tight fit	15.1 tok/s	15132 ms	33K
RAG	B	Tight fit	15.1 tok/s	23280 ms	33K

Quantization options

How Mixtral 8x7B (47B params) fits at each quantization level on MacBook Pro M4 Pro 64GB (46.1 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	18.3 GB	Low	B62
Q3_K_S	3	23.0 GB	Low	B64
NVFP4	4	26.3 GB	Medium	B64
Q4_K_M	4	28.7 GB	Medium	B63
Q5_K_MBest for your GPU	5	33.8 GB	High	B63
Q6_K	6	38.5 GB	High	F0
Q8_0	8	50.3 GB	Very High	F0
F16	16	96.4 GB	Maximum	F0