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URL: https://willitrunai.com/can-run/mixtral-8x7b-on-radeon-pro-w7900-ds-48gb

⇱ Mixtral 8x7B on Radeon PRO W7900 DS 48GB? YES

Can Mixtral 8x7B run on Radeon PRO W7900 DS 48GB?

YES — Runs Great

B69Good
○Estimated from fit model

Mixtral 8x7B needs ~36.3 GB VRAM. Radeon PRO W7900 DS 48GB has 48.0 GB. With Q4_K_M quantization, expect ~37 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 36.3 GB, 36.7 tok/s, Runs well
36.3 GB required48.0 GB available
76% VRAM used

Fit status

Runs well

Decode

36.7 tok/s

TTFT

5280 ms

Safe context

33K

Memory

36.3 GB / 48.0 GB

Memory breakdown

Weights28.7 GB
KV Cache2.0 GB
Runtime0.9 GB
Headroom4.8 GB

See how fast it feels

See how fast it feelsMixtral 8x7B on Radeon PRO W7900 DS 48GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 36.7 tok/s decode · 5.3s TTFT (warm) · 92 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatBRuns well36.7 tok/s2880 ms33K
CodingBRuns well36.7 tok/s5280 ms33K
Agentic CodingBRuns well36.7 tok/s7680 ms33K
ReasoningBRuns well36.7 tok/s6240 ms33K
RAGBRuns well36.7 tok/s9600 ms33K

Quantization options

How Mixtral 8x7B (47B params) fits at each quantization level on Radeon PRO W7900 DS 48GB (48.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
18.3 GB
LowB61
Q3_K_S
3
23.0 GB
LowB63
NVFP4
4
26.3 GB
MediumB64
Q4_K_M
4
28.7 GB
MediumB63
Q5_K_M
5
33.8 GB
HighB63
Q6_KBest for your GPU
6
38.5 GB
HighB63
Q8_0
8
50.3 GB
Very HighF0
F16
16
96.4 GB
MaximumF0

Get started

Copy-paste commands to run Mixtral 8x7B on your machine.

Run

ollama run mixtral

Upgrade options

Hardware that runs Mixtral 8x7B well

AMD Instinct MI210 64GBBudget pick
64 GB VRAM (+16)1638 GB/s (+774)
B
Raises estimated decode speed by about 118%.80.1 tok/s decode

Raises estimated decode speed by about 118%.

Adds memory headroom for longer context windows and future model growth.

~$10,000 MSRP

Frequently asked questions

See all results for Radeon PRO W7900 DS 48GBSee all hardware for Mixtral 8x7B