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URL: https://willitrunai.com/can-run/phi-3-medium-14b-on-instinct-mi210-64gb


Can Phi 3 Medium 14B run on AMD Instinct MI210 64GB?

YES — Runs Great

B59Good
Estimated from fit model

Phi 3 Medium 14B needs ~18.9 GB VRAM. AMD Instinct MI210 64GB has 64.0 GB. With Q4_K_M quantization, expect ~140 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 18.9 GB, 140.2 tok/s, Runs well
18.9 GB required64.0 GB available
30% VRAM used

Fit status

Runs well

Decode

140.2 tok/s

TTFT

1381 ms

Safe context

128K

Memory

18.9 GB / 64.0 GB

Memory breakdown

Weights8.5 GB
KV Cache3.1 GB
Runtime0.9 GB
Headroom6.4 GB

See how fast it feels

See how fast it feelsPhi 3 Medium 14B on AMD Instinct MI210 64GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 140.2 tok/s decode · 1.4s TTFT (warm) · 351 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatBRuns well140.2 tok/s753 ms128K
CodingBRuns well140.2 tok/s1381 ms128K
Agentic CodingBRuns well140.2 tok/s2008 ms128K
ReasoningBRuns well140.2 tok/s1632 ms128K
RAGBRuns well140.2 tok/s2511 ms128K

Quantization options

How Phi 3 Medium 14B (14B params) fits at each quantization level on AMD Instinct MI210 64GB (64.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
5.5 GB
LowC52
Q3_K_S
3
6.9 GB
LowC52
NVFP4
4

Get started

Copy-paste commands to run Phi 3 Medium 14B on your machine.

Run

ollama run phi3:medium

Frequently asked questions

See all results for AMD Instinct MI210 64GBSee all hardware for Phi 3 Medium 14B
7.8 GB
Medium
C52
Q4_K_M
4
8.5 GB
MediumC52
Q5_K_M
5
10.1 GB
HighC52
Q6_K
6
11.5 GB
HighC52
Q8_0
8
15.0 GB
Very HighC53
F16Best for your GPU
16
28.7 GB
MaximumB56