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URL: https://willitrunai.com/compare?a=instinct-mi325x-256gb&b=instinct-mi300x-192gb

⇱ Compare GPUs for Local AI — Side-by-Side Hardware Analysis | Will It Run AI

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Compare local AI hardware with workload-aware output.

AMD Instinct MI325X 256GB wins for coding in balanced mode

Based on model fit, speed, and quality across top recommendations.

AMD Instinct MI325X 256GB

Winner
SDeepSeek V4 Flash
llama.cppNVFP4Runs well
185.8 GB / 256.0 GB
94.4 tok/s872K ctx
SDevstral 2 123B Instruct
llama.cppQ4_K_MRuns well
106.9 GB / 256.0 GB
63.5 tok/s256K ctx
SMiniMax M2.7
llama.cppUD-IQ4_XSRuns well
170.6 GB / 256.0 GB
101.4 tok/s205K ctx

Quick comparison

MetricAMD Instinct MI325X 256GBAMD Instinct MI300X 192GB
Models that fit33
Avg decode tok/s86.4135.4
Best grade score9995

Operating mode: Balanced. Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

AMD Instinct MI300X 192GB

SDevstral 2 123B Instruct
llama.cppQ4_K_MRuns well
100.5 GB / 192.0 GB
59.9 tok/s256K ctx
SQwen 3.5 122B A10B
llama.cppQ4_K_MRuns well
97.0 GB / 192.0 GB
166.2 tok/s131K ctx
SMistral Small 4 119B
llama.cppQ4_K_MRuns well
98.1 GB / 192.0 GB
180.2 tok/s256K ctx