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⇱ AI Models for AMD Instinct MI60 32GB — What Runs on 32GB VRAM


AMD

AMD Instinct MI60 32GB

InstinctDatacenterVegaPCIe 4ROCm

Operating mode

Choose the operating mode for this hardware

Use this to bias workload recommendations toward responsiveness, background autonomy, lighter serving, or multi-GPU scale-out.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

See Full AI Tier List for AMD Instinct MI60 32GB →

About this GPU for AI

The AMD Instinct MI60 32GB is an older Vega-based datacenter GPU from 2018, one of AMD's first serious HPC accelerators. While it has full ROCm support (being a datacenter Instinct card), the Vega architecture is old and the 29 TFLOPS FP16 compute is very modest by modern standards. The 32 GB of HBM2 VRAM is its main AI asset, but newer Instinct cards offer dramatically better compute at lower cost on the used market.

Beyond LLMs

AI Capability Matrix

What AI tasks this GPU can handle — from text generation to image and video creation.

CapabilityStatusRepresentative ModelDetail
LLM Chat (7B)Runs nativelyLlama 3.1 8B Q4
LLM Coding (30B)Runs nativelyQwen 3 30B Q4
LLM Large (70B)
rocm-supporteddatacenter-gradelegacyhigh-bandwidth

Specifications

Compute
FP1629 TFLOPS
INT858 TOPS
ArchitectureVega
Memory
VRAM32 GB
Bandwidth1024 GB/s
General
FamilyInstinct
SegmentDatacenter
InterconnectPCIe 4
Compute PlatformROCM
MSRP$8,999

Key Features

Vega (GCN 5) architecture — AMD's HPC-focused Vega 20 die32 GB HBM2 on a 4096-bit bus1 TB/s memory bandwidthFull ROCm support — Instinct datacenter cardPCIe Gen 3/4 x16Legacy ROCm support may require older toolchain versions

For AI Workloads

Strengths
  • Full ROCm support as an Instinct datacenter card
  • 32 GB HBM2 with 1 TB/s bandwidth — memory bandwidth is a strength
  • HBM2 delivers very high bandwidth for memory-bandwidth-bound inference
  • Full ROCm software stack compatible
Considerations
  • 29 TFLOPS FP16 is very low compute — slow token generation
  • Vega architecture is significantly older than CDNA — less efficient AI kernels
  • Newer ROCm versions may drop or reduce support for legacy Vega
  • MI100 or MI210 are far better choices for actual AI workloads

Architecture

Vega

Vega is AMD's GCN 5th generation architecture, featuring HBM2 memory and high compute density. Used in consumer Vega cards and the Instinct MI60 datacenter accelerator.

AI Relevance

The Instinct MI60 with 32 GB HBM2 and ROCm support can run LLM inference, but its age means limited compatibility with modern AI frameworks. Consumer Vega cards have insufficient VRAM for meaningful AI work.

Process: GlobalFoundries 14nmPlatform: ROCMPrecisions: FP64, FP32, FP16

Recommendations by Workload

Chat

S

Qwen 3.5 35B A3B

Qwen 3.5 35B A3B matches Chat and keeps a practical fit profile. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, ollama, lm-studio.

Decode 69.3 tok/s · 72K ctx · llama.cppEST.
26.2 GB / 32.0 GB VRAM

Coding

S

Qwen 3.6 27B

Qwen 3.6 27B is a specialized fit for Coding. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, lm-studio.

Decode 20.5 tok/s · 187K ctx · llama.cppEST.
21.5 GB / 32.0 GB VRAM

Agentic Coding

S

Full Model Compatibility

👁 Alibaba
Qwen3-Coder 30B A3B Instruct
S99
30.5B24.2 GB76 tok/s102K ctx
moe
👁 Alibaba
Qwen3-VL 30B A3B Instruct
S99
30B23.9 GB79 tok/s105K ctx
moe
👁 Alibaba
Qwen 3 30B A3B
S97

Just out of reach

Models you could run with an upgrade

High-quality models that need a bit more memory

Image & Video Generation

Diffusion Model Compatibility

43 of 52 models can generate images or video on your AMD Instinct MI60 32GB

ModelMax ResolutionGen TimeGrade
SD TurboImage512×512~2.2sS
Stable Diffusion 1.5Image512×768~4.4sS
Realistic Vision v5.1Image512×768~4.4sS
DreamShaper 8Image512×768~4.4sS
LCM DreamShaper v7

Upgrade paths

Upgrade from AMD Instinct MI60 32GB

See what you unlock with more powerful hardware

Upgrade options

Upgrade options

MacBook Pro M1 Max 64GBNext step up
64 GB Unified (+32)
A
Unlocks 11 additional models that do not fit on the current setup.Unlocks Qwen 2.5 VL 72B, Llama 3.3 70B, Llama 3.1 70B+8 more

Unlocks 11 additional models that do not fit on the current setup.

~$2,499 MSRP

Radeon PRO W7900 DS 48GBAMD upgrade
48 GB VRAM (+16)
A
Unlocks 13 additional models that do not fit on the current setup.Unlocks Qwen 2.5 VL 72B, Qwen3-Coder-Next, Llama 3.3 70B+10 more

Unlocks 13 additional models that do not fit on the current setup.

~$3,999 MSRP

MacBook Pro M3 Max 128GBBest value
128 GB Unified (+96)
B
Unlocks 26 additional models that do not fit on the current setup.Unlocks Devstral 2 123B Instruct, Qwen 3.5 122B A10B, Mistral Small 4 119B+23 more

Unlocks 26 additional models that do not fit on the current setup.

~$2,499 MSRP

AMD Instinct MI350X 288GBBiggest leap
288 GB VRAM (+256)8000 GB/s (+6976)
B
Unlocks 39 additional models that do not fit on the current setup.Unlocks Qwen 3.5 397B A17B, Devstral 2 123B Instruct, Qwen 3.5 122B A10B+36 more · +144% faster avg

Unlocks 39 additional models that do not fit on the current setup.

Lifts average decode speed across fitting models by about 144%.

~$8,000 MSRP

Frequently Asked Questions

Compare with similar

AMD Instinct MI60 32GB vs RTX 5090 32GBAMD Instinct MI60 32GB vs RTX 5000 Ada 32GBAMD Instinct MI60 32GB vs RTX PRO 4500 Blackwell 32GB
Compare this GPUCompare with another GPU →
32GB
VRAM
1kGB/s
Bandwidth
29TFLOPS
FP16 Compute
58TOPS
INT8 Inference
$8,999 MSRP
AMD Instinct MI60 32GBCategory AvgMacBook Pro M1 Max 64GB
Won’t fit
Llama 3.1 70B Q4
Image Gen (SDXL)Runs nativelySDXL 1.0 FP16~~17.5s per image
Image Gen (Flux)Runs nativelyFlux.1 Dev FP16~~2m 18s per image
Image Gen (SD 3.5)Runs nativelySD 3.5 Large FP16~~1m 37s per image
Video Short (25f)Runs nativelyLTX Video 2B~~15.2s/frame
Video Long (100f)Won't fitWan Video 14B~~44.8s/frame

Qwen 3.6 27B

Qwen 3.6 27B is a specialized fit for Agentic Coding. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, lm-studio.

Decode 20.5 tok/s · 187K ctx · llama.cppEST.
22.5 GB / 32.0 GB VRAM

Reasoning

S

Devstral Small 2 24B Instruct

Devstral Small 2 24B Instruct matches Reasoning and keeps a practical fit profile. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, ollama, lm-studio.

Decode 36.8 tok/s · 87K ctx · llama.cppEST.
21.2 GB / 32.0 GB VRAM

RAG

S

Qwen 3.5 27B

Qwen 3.5 27B matches RAG and keeps a practical fit profile. It is a recent-generation family, which helps on current local SOTA workloads. It should run, but memory headroom will be limited. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, ollama, lm-studio.

Decode 32.9 tok/s · 58K ctx · llama.cppEST.
26.9 GB / 32.0 GB VRAM
30.5B24.2 GB76 tok/s102K ctx
moe
👁 Alibaba
Qwen 3.5 27B
S96
27B23.7 GB33 tok/s58K ctx
dense
👁 Alibaba
Qwen 3.6 35B A3B
S95
35B29.6 GB64 tok/s26K ctx
+1moe
👁 Mistral
Magistral Small 2507
S95
24B21.2 GB37 tok/s87K ctx
dense
👁 Alibaba
Qwen 3.5 35B A3B
S95
35B26.9 GB69 tok/s72K ctx
moe
👁 Mistral
Devstral Small 2 24B Instruct
S94
24B21.2 GB37 tok/s87K ctx
dense
👁 NVIDIA
Nemotron Cascade 2 30B A3B
S94
30B25.3 GB78 tok/s52K ctx
moe
👁 Alibaba
Qwen 3.6 27B
S94
27B21.5 GB21 tok/s187K ctx
+1dense
👁 OpenAI
GPT-OSS 20B
S93
21B19.4 GB96 tok/s99K ctx
moe
👁 NVIDIA
Nemotron 3 Nano 30B
S93
30B24.8 GB30 tok/s63K ctx
dense
👁 Mistral
Devstral Small 1.1
S93
24B21.2 GB37 tok/s87K ctx
dense
👁 Google
Gemma 4 26B A4B
S92
25.2B23.1 GB82 tok/s55K ctx
moe
👁 Alibaba
Qwen 3 14B
S92
14B15.1 GB64 tok/s127K ctx
dense
👁 Alibaba
Qwen 3.5 9B
S91
9B11.8 GB98 tok/s131K ctx
dense
👁 Alibaba
Qwen 3 32B
S91
32B27.5 GB28 tok/s34K ctx
dense
👁 Microsoft
Phi-4-reasoning-plus 14B
S91
14.7B16.1 GB60 tok/s33K ctx
dense
👁 Alibaba
Qwen 3 8B
S89
8B11.2 GB111 tok/s131K ctx
dense
👁 Alibaba
Qwen 3.5 4B
S86
4B8.7 GB56 tok/s131K ctx
dense
👁 Mistral
Ministral 3 14B
S86
14B15.1 GB63 tok/s127K ctx
multimodal
👁 LG AI
EXAONE 4.0 32B
S85
32B27.5 GB28 tok/s34K ctx
dense
👁 NVIDIA
Nemotron Nano 8B
A84
8B10.9 GB111 tok/s131K ctx
dense
👁 Microsoft
Phi-4 Mini Reasoning 4B
A83
3.8B7.9 GB53 tok/s131K ctx
dense
👁 Jina AI
Jina Embeddings v3
A76
0.57B7.2 GB8 tok/s8K ctx
dense
👁 BAAI
BGE M3
A74
0.57B6.4 GB8 tok/s8K ctx
dense
👁 Google
Gemma 4 31B
A73
30.7B37.5 GB9 tok/s10K ctx
dense
👁 Alibaba
Qwen 3.5 397B A17B
F0
397B249.1 GB2 tok/s4K ctx
moe
👁 Mistral
Devstral 2 123B Instruct
F0
123B84.5 GB2 tok/s4K ctx
dense
👁 Moonshot AI
Kimi K2.5
F0
1000B621.5 GB2 tok/s4K ctx
moe
👁 Moonshot AI
Kimi K2.6
F0
1000B621.5 GB2 tok/s4K ctx
+1moe
👁 DeepSeek
DeepSeek V4 Pro
F0
1600B868.0 GB2 tok/s4K ctx
moe
👁 Alibaba
Qwen 3.5 122B A10B
F0
122B81.0 GB3 tok/s4K ctx
moe
👁 DeepSeek
DeepSeek V4 Flash
F0
284B163.4 GB2 tok/s4K ctx
moe
👁 Mistral
Mistral Small 4 119B
F0
119B82.1 GB3 tok/s4K ctx
moe
👁 Cohere
Command A 111B
F0
111B75.7 GB2 tok/s4K ctx
dense
👁 Alibaba
Qwen 2.5 VL 72B
F0
72B52.9 GB3 tok/s4K ctx
dense
👁 OpenAI
GPT-OSS 120B
F0
117B80.4 GB2 tok/s4K ctx
dense
👁 Alibaba
Qwen3-Coder-Next
F0
80B54.4 GB8 tok/s4K ctx
moe
👁 Z.ai
GLM-5.1
F0
754B483.1 GB2 tok/s4K ctx
moe
👁 Mistral AI
Pixtral Large 124B
F0
124B85.1 GB2 tok/s4K ctx
dense
👁 Z.ai
GLM-5
F0
744B477.0 GB2 tok/s4K ctx
moe
👁 DeepSeek
DeepSeek V3.2
F0
671B413.9 GB2 tok/s4K ctx
moe
👁 Alibaba
Qwen 3 235B A22B
F0
235B150.3 GB2 tok/s4K ctx
moe
👁 Alibaba
Qwen3-Coder 480B A35B Instruct
F0
480B299.8 GB2 tok/s4K ctx
moe
MiniMax M2.7
F0
230B148.2 GB2 tok/s4K ctx
moe
👁 Mistral
Leanstral 119B A6B
F0
119B85.5 GB3 tok/s4K ctx
moe
👁 DeepSeek
DeepSeek Coder V2 236B
F0
236B206.7 GB2 tok/s4K ctx
moe
👁 DeepSeek
DeepSeek R1 671B
F0
671B473.0 GB2 tok/s4K ctx
moe
👁 DeepSeek
DeepSeek V3.1 671B
F0
671B473.0 GB2 tok/s4K ctx
moe
Image
512×768
~1.3s
S
PixArt-SigmaImage1024×1024~17.5sS
FramePack I2VVideo256×256~32.2s/frameS
SDXL TurboImage512×512~2.2sS
SDXL LightningImage1024×1024~6.6sS
Stable Diffusion XL 1.0Image1024×1024~17.5sS
Playground v2.5Image1024×1024~26.3sS
RealVisXL v5.0Image1024×1024~19.7sS
DreamShaper XLImage1024×1024~19.7sS
Juggernaut XL v9Image1024×1024~19.7sS
Animagine XL 3.1Image1024×1024~19.7sS
Pony Diffusion V6 XLImage1024×1024~19.7sS
Animagine XL 4.0Image1024×1024~19.7sS
Illustrious XLImage1024×1024~19.7sS
Wan Video 2.1 1.3BVideo480×832~12.8s/frameS
Stable Diffusion 3.5 MediumImage1024×1024~30.7sS
Flux.2 Klein 4BImage1024×1024~5.3sS
LTX Video 2BVideo1280×720~15.2s/frameS
KolorsImage1024×1024~35.1sS
Stable CascadeImage1024×1024~43.9sS
AuraFlow v0.3Image1536×1536~1m 19sS
Stable Diffusion 3.5 LargeImage1024×1024~1m 37sS
Stable Diffusion 3.5 Large TurboImage1024×1024~17.5sS
CogVideoX 2BVideo720×480~15.2s/frameS
HunyuanVideoVideo256×256~32.2s/frameS
ChromaImage1024×1024~17.5sS
Z-Image TurboImage1536×1536~18.1sS
Flux.1 DevImage256×256~2m 18sS
Flux.1 SchnellImage256×256~26.9sS
LTX Video 13BVideo256×256~32.2s/frameS
Flux.1 Kontext DevImage256×256~2m 34sS
AnimateDiff v1.5.3Video512×768~8s/frameS
Cosmos Diffusion 7BVideo1024×576~25.1s/frameA
CogVideoX 5BVideo720×480~22s/frameA
Wan2.2 TI2V 5BVideo832×480~22s/frameA
Flux.2 Klein 9BImage1024×1024~8.8sA
Flux.1 Fill DevImage256×256~2m 11sB
Mochi 1 PreviewVideo256×256~52.2s/frameD
HunyuanVideo 1.5Video256×256~50.1s/frameD
Helios 14BVideo256×256~33.2s/frameF
SkyReels V2 14BVideo256×256~33.2s/frameF
Wan Video 2.1 14BVideo256×256~33.2s/frameF
Wan Video 2.2 14BVideo256×256~33.2s/frameF
Qwen ImageImage256×256~29.5sF
Qwen Image EditImage256×256~29.5sF
Flux.2 DevImage256×256~13m 50sF
MAGI-1Video256×256~41.2s/frameF
HunyuanImage 3.0Image256×256~52sF

Image models estimated at 1024×1024 (28 steps, FP16). Video models estimated at 768×512 (25 frames, 30 steps, FP16). Actual performance varies with runtime and system load.

Buying advice

Should you buy AMD Instinct MI60 32GB for local AI?

Excellent choice for local AI

Runs 27 of 50 top models well — a strong all-rounder for local inference.

32.0 GB

VRAM

$8,999

MSRP

$281/GB

Cost per GB VRAM

Best models for this GPU

What will limit you first

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best upgrade itinerary

Unlocks 11 additional models that do not fit on the current setup.

Want more headroom? MacBook Pro M1 Max 64GB (64.0 GB unified memory) is the next step up.