Drug Discovery
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Drug Discovery
This course is part of Drug Development Product Management Specialization
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3,948 reviews
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There are 6 modules in this course
The University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences Drug Discovery course brings you lectures from both faculty and industry experts. With this course, recorded on campus at UCSD, we seek to share our access to top people in the field who bring an unprecedented range of expertise on drug discovery.
In this course you will learn the drug discovery process up to the filing of an Initial New Drug Application or IND. Each week you will learn the steps that a pharmaceutical or biotech company goes through to discover a new therapeutic drug. In this course you will be able to: * Understand the pharmaceutical and biotechnology market a changing landscape * Learn the major aspects of the drug discovery process, starting with target selection, to compound screening to designing lead candidates. * Recognize current modern drug discovery based on the lock-and-key theory, which attempts to use one single compound to hit one target to combat the related disease. * Increase understanding of the various drug discovery tools and methods that are used for finding, identifying and designing a new drug. * Define and understand the regulatory responsibilities for drug discovery to file an Investigational New Drug Application (IND). This course is intended as part 1 of a series: Drug Discovery, Drug Development (https://www.coursera.org/learn/drug-development) and Drug Commercialization (https://www.coursera.org/learn/drug-commercialization). We would highly recommend that you take the courses in order since it will give you a better understanding on how a drug is discovered in the lab before being tested in clinical trials and then launched in the market place.
What's included
1 video1 discussion prompt
1 videoβ’Total 3 minutes
- Welcome!β’3 minutes
1 discussion promptβ’Total 10 minutes
- Get to know your fellow Courserians!β’10 minutes
In this module course lead Dr. Williams Ettouati begins by giving a landscape overview of the Pharma and Biotechnology landscape.
What's included
7 videos3 readings1 assignment2 discussion prompts
7 videosβ’Total 70 minutes
- Pharma and Biotechnology Landscapeβ’9 minutes
- Key Issues for Pharmaβ’11 minutes
- Global Outlook: What will the Future Look Like?β’11 minutes
- Creating a Sustainable Businessβ’13 minutes
- Patient-Centric Drug Discovery and Commercializationβ’9 minutes
- A New Approach to R&Dβ’10 minutes
- Innovation and Its Role in Developing Better Drugsβ’7 minutes
3 readingsβ’Total 15 minutes
- Meet the Instructorsβ’5 minutes
- Lecture Slidesβ’0 minutes
- A new Master Degree in Science in Drug Development & Product Management at UCSDβ’10 minutes
1 assignmentβ’Total 30 minutes
- Pharma and Biotechβ’30 minutes
2 discussion promptsβ’Total 20 minutes
- Mega-mergers: What are their implications?β’10 minutes
- Pharma and Biotech Changesβ’10 minutes
This week we will be hearing from Phillip Bourne, PhD. Dr. Bourne was, at the time of this recording, the Associate Vice Chancellor for Innovation and Industrial Alliances in the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Since that time, he has been named the first Associate Director for Data Science at the United States National Institutes of Health.
What's included
5 videos1 reading1 assignment1 discussion prompt
5 videosβ’Total 50 minutes
- Drug Discovery: Proteomics, Genomics Iβ’10 minutes
- Drug Discovery: Proteomics, Genomics IIβ’12 minutes
- Drug Discovery: Proteomics, Genomics IIIβ’9 minutes
- Drug Discovery: Proteomics, Genomics IVβ’9 minutes
- Drug Discovery: Proteomics, Genomics Vβ’10 minutes
1 reading
- Lecture Slidesβ’0 minutes
1 assignmentβ’Total 30 minutes
- Drug Discovery: Proteomics, Genomicsβ’30 minutes
1 discussion promptβ’Total 10 minutes
- What's the most interesting thing discussed this module?β’10 minutes
This week we will hear from Ronald Christopher, Ph.D. Dr. Ronald Christopher, Vice President of Preclinical Trials at Arena Pharmaceuticals.
What's included
6 videos1 reading1 assignment2 discussion prompts
6 videosβ’Total 62 minutes
- Compound Selection & Preclinical Studies Iβ’11 minutes
- Compound Selection & Preclinical Studies IIβ’10 minutes
- Compound Selection & Preclinical Studies IIIβ’8 minutes
- Compound Selection & Preclinical Studies IVβ’11 minutes
- Compound Selection & Preclinical Studies Vβ’9 minutes
- Compound Selection & Preclinical Studies VIβ’13 minutes
1 reading
- Lecture Slidesβ’0 minutes
1 assignmentβ’Total 30 minutes
- Compound Selection and Pre-clinical Studiesβ’30 minutes
2 discussion promptsβ’Total 20 minutes
- Efforts in Drug Discovery: Differences between first-in-class and best-in-classβ’10 minutes
- Develop your own first-in-class drugβ’10 minutes
In this module we will hear from Stephen Burley, M.D., Ph.D. At the time of this recording, Director of the Center for Integrative Proteomics at Rutgers University. He is now the Director of the Protein Data Bank and remains an Adjunct Professor at the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences.
What's included
5 videos2 readings1 assignment2 discussion prompts
5 videosβ’Total 50 minutes
- Challenges in Fragment Based Drug Discovery for Protein Kinases Iβ’10 minutes
- Challenges in Fragment Based Drug Discovery for Protein Kinases IIβ’10 minutes
- Challenges in Fragment Based Drug Discovery for Protein Kinases IIIβ’11 minutes
- Challenges in Fragment Based Drug Discovery for Protein Kinases IVβ’10 minutes
- Challenges in Fragment Based Drug Discovery for Protein Kinases Vβ’9 minutes
2 readingsβ’Total 3 minutes
- Optional: Examples using structure based approachesβ’3 minutes
- Lecture Slidesβ’0 minutes
1 assignmentβ’Total 30 minutes
- Challenges in Fragment Based Drug Discovery for Protein Kinasesβ’30 minutes
2 discussion promptsβ’Total 20 minutes
- Collaboration among scientific disciplines - how important is it?β’10 minutes
- Clinical Trials Interruptions: What can we learn?β’10 minutes
This module we hear from Professor of Clinical Pharmacy and Pediatrics, Brookie Best, Pharm. D., of UCSD's Skaggs School of Pharmacy and Pharmaceutical Sciences.
What's included
5 videos1 reading1 assignment1 discussion prompt
5 videosβ’Total 47 minutes
- Key Concepts in Drug Delivery Iβ’9 minutes
- Key Concepts in Drug Delivery IIβ’10 minutes
- Key Concepts in Drug Delivery IIIβ’10 minutes
- Key Concepts in Drug Delivery IVβ’10 minutes
- Key Concepts in Drug Delivery Vβ’7 minutes
1 reading
- Lecture Slidesβ’0 minutes
1 assignmentβ’Total 30 minutes
- Concepts in Drug Delivery Quizβ’30 minutes
1 discussion promptβ’Total 10 minutes
- How did this course help you?β’10 minutes
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Reviewed on Nov 7, 2020
As a pharmaceutical sciences student, this course was extremely helpful and interesting, the materials covered answered many of the questions I had in regards to the topic !
Reviewed on May 25, 2020
This course will help me in getting an idea about research for new drugs and site targets ,as well as which route is effective for administration of what type of drugs.
Reviewed on Nov 14, 2020
This course gives a very nice introduction into different considerations of drug development. Altough it is a bit older, I feel the topics are still relevant and up to date.
Frequently asked questions
To access the course materials, assignments and to earn a Certificate, you will need to purchase the Certificate experience when you enroll in a course. You can try a Free Trial instead, or apply for Financial Aid. The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.
When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile.
Yes. In select learning programs, you can apply for financial aid or a scholarship if you canβt afford the enrollment fee. If fin aid or scholarship is available for your learning program selection, youβll find a link to apply on the description page.
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