Generative AI and Blockchain
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There are 4 modules in this course
This course explores the transformative potential of artificial intelligence (AI) and blockchain, specifically focusing on how they intersect in the Web3 era. We'll begin by examining the evolution of the Internetβfrom the early days of Web1 to the emergence of Web3. You'll look at the layers of the Web3-AI stack, and some of the unique opportunities and challenges that AI faces in the Web3 era. In Module 2, we'll explore how blockchain can make Generative AI more transparent, secure, and reliable, and how Generative AI can enhance what blockchains doβfrom automating smart contracts to optimizing networks and creating personalized experiences. In Module 3, we'll look beyond Generative AI and explore other areas where AI and blockchain intersect, including Agentic AI, decentralized governance, and AI-driven tokenomics. Finally, in Module 4, weβll examine some real-world use cases in healthcare, arts and media, global commerce, energy, and sustainability. Youβll see how blockchain and AI work together to improve security, transparency, and adaptability across industries, delivering benefits to both businesses and users alike.
In Module 1, you will be introduced to the concept of Web3, the next era of the internet, and how it builds upon previous eras of the Web. You'll learn how Web3 aims to cultivate a more open, transparent, and decentralized online experience, leveraging blockchain to empower users with control over their digital assets, data, and identities. You will also learn about decentralization across three primary levels: value, infrastructure, and organizations. We'll discuss how decentralization returns power and control to users, enabling them to own and manage their data and assets, actively participate in governance processes, and benefit from more resilient and accessible online services. We will then focus on the intersection of blockchain and AI, examining the six layers of the Web3-AI ecosystem: decentralized infrastructure, data fabric, foundation models, domain-specific models, smart contracts, and applications. Finally, we will look at both the opportunities and challenges that arise when AI and blockchain intersect in a Web3 world.
What's included
7 videos3 readings5 assignments1 discussion prompt
7 videosβ’Total 60 minutes
- Course Introductionβ’9 minutes
- What is Web3?β’8 minutes
- Decentralization in the Web3 Eraβ’16 minutes
- Layers of the Web3-AI Ecosystemβ’9 minutes
- Opportunities for AI in a Web3 Worldβ’9 minutes
- Challenges for AI in a Web3 Worldβ’7 minutes
- Module Recapβ’3 minutes
3 readingsβ’Total 105 minutes
- The Rise of Web3β’60 minutes
- Layers of the Web3-AI Ecosystemβ’15 minutes
- AI in a Web3 Worldβ’30 minutes
5 assignmentsβ’Total 75 minutes
- AI in a Web3 Worldβ’30 minutes
- The Rise of Web3β’10 minutes
- Decentralization in the Web3 Eraβ’10 minutes
- Layers of the Web3-AI Ecosystemβ’10 minutes
- AI in a Web3 Worldβ’15 minutes
1 discussion promptβ’Total 10 minutes
- Introduce Yourselfβ’10 minutes
In this module, you will learn how blockchain and generative AI can work together to improve each other and create innovative solutions across various industries. We will first examine how blockchain can enhance generative AI by providing a secure and transparent infrastructure for data integrity and provenance, enabling trusted federated learning, and improving AI decision-making. Then, you will explore how generative AI can, in turn, enhance blockchain technology by automating smart contract creation, personalizing decentralized applications while respecting user privacy, generating unique digital assets like NFTs, optimizing blockchain networks, and simplifying blockchain interactions for users. Finally, we will consider real-world examples of this synergy in sectors like arts and media, real estate, gaming, risk assessment, and supply chain management.
What's included
5 videos3 readings4 assignments
5 videosβ’Total 31 minutes
- Module Overviewβ’3 minutes
- How Blockchain Improves Generative AIβ’8 minutes
- How Generative AI Improves Blockchainβ’8 minutes
- How Generative AI and Blockchain Work Togetherβ’9 minutes
- Module Recapβ’3 minutes
3 readingsβ’Total 40 minutes
- How Blockchain Improves Generative AIβ’20 minutes
- How Generative AI Improves Blockchainβ’10 minutes
- How Generative AI and Blockchain Work Togetherβ’10 minutes
4 assignmentsβ’Total 65 minutes
- Generative AI and Blockchainβ’30 minutes
- How Blockchain Improves Generative AIβ’10 minutes
- How Generative AI Improves Blockchainβ’15 minutes
- How Generative AI and Blockchain Work Togetherβ’10 minutes
In this module, you will expand your knowledge of AI beyond generative AI to explore how the broader AI landscape intersects with blockchain in a Web3 world. We will first consider "Agentic AI," which describes AI systems designed to autonomously pursue complex goals and workflows with limited direct human supervision. You will learn how blockchain can enhance the security and trustworthiness of these AI agents. Next, we will examine how AI can be used to facilitate and improve operations and decision-making in Decentralized Autonomous Organizations (DAOs), and the importance of balancing AI capabilities with human input in decentralized governance. We will also discuss some of the ethical considerations and challenges associated with AI and blockchain. Finally, you will learn how AI can be used to transform blockchain economics through AI-driven tokenomics and incentive structures.
What's included
5 videos3 readings4 assignments
5 videosβ’Total 37 minutes
- Module Overviewβ’4 minutes
- Agentic AIβ’13 minutes
- Collaborative AI and Decentralized Governanceβ’9 minutes
- AI-Driven Tokenomics and Incentive Structuresβ’7 minutes
- Module Recapβ’5 minutes
3 readingsβ’Total 60 minutes
- Agentic AIβ’20 minutes
- Collaborative AI and Decentralized Governanceβ’20 minutes
- AI-Driven Tokenomics and Incentive Structuresβ’20 minutes
4 assignmentsβ’Total 65 minutes
- AI-Driven Tokenomics and Incentive Structuresβ’30 minutes
- Agentic AIβ’15 minutes
- Collaborative AI and Decentralized Governanceβ’10 minutes
- AI-Driven Tokenomics and Incentive Structuresβ’10 minutes
In this module, you will explore how the intersection of AI and blockchain can be used to transform various industries. In healthcare, you will learn how AI and blockchain can personalize medicine, streamline clinical trials, and improve drug development and healthcare operations. In arts and media, you will discover how blockchain can be used to verify the authenticity of digital content, ensure fair compensation for creators, and create new interactive experiences. Next, we will examine global commerce and explore how AI and blockchain can streamline cross-border payments, customs clearance, and logistics, as well as enhance ESG tracking and transparency. Finally, we will look at the energy and sustainability sector, where you will learn how AI and blockchain are being used to create decentralized energy markets, optimize grid resilience, and encourage energy efficiency.
What's included
7 videos4 readings5 assignments
7 videosβ’Total 56 minutes
- Module Overviewβ’4 minutes
- Healthcare in a Web3 Worldβ’11 minutes
- Arts and Media in a Web3 Worldβ’10 minutes
- Global Commerce in a Web3 Worldβ’9 minutes
- Energy and Sustainability in a Web3 Worldβ’9 minutes
- Module Recapβ’5 minutes
- Course Close and Thank Youβ’7 minutes
4 readingsβ’Total 120 minutes
- Healthcare in a Web3 Worldβ’30 minutes
- Arts and Media in a Web3 Worldβ’30 minutes
- Global Commerce in a Web3 Worldβ’30 minutes
- Energy and Sustainability in a Web3 Worldβ’30 minutes
5 assignmentsβ’Total 65 minutes
- Industry Applications and Case Studiesβ’30 minutes
- Healthcare in a Web3 Worldβ’10 minutes
- Arts and Media in a Web3 Worldβ’10 minutes
- Global Commerce in a Web3 Worldβ’10 minutes
- Energy and Sustainability in a Web3 Worldβ’5 minutes
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Reviewed on May 5, 2026
It is a bit theoretical, could it be more practical?
Reviewed on Mar 27, 2026
Good course taught by known experts in Blockchain. But the course didn't use AI or Blockchain. AI can be used for coaching and testing. Blockchain can be used to store education certificates.
Reviewed on Jul 6, 2025
An interesting and very worthwhile course to obtain a good understanding of Generative AI and Blockchain
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Yes. In select learning programs, you can apply for financial aid or a scholarship if you canβt afford the enrollment fee. If fin aid or scholarship is available for your learning program selection, youβll find a link to apply on the description page.
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