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Population Health: Study Design

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Gain insight into a topic and learn the fundamentals.
4.3

21 reviews

Intermediate level
Some related experience required
3 weeks to complete
at 10 hours a week
Flexible schedule
Learn at your own pace

Gain insight into a topic and learn the fundamentals.
4.3

21 reviews

Intermediate level
Some related experience required
3 weeks to complete
at 10 hours a week
Flexible schedule
Learn at your own pace

What you'll learn

  • You will be able to formulate a good research question

  • You will be able to interpret and apply different frequency and effect measures

  • You will be able to recognize errors and deal with bias and confounding

  • You will be able to describe basic principles of causal inference

Details to know

Shareable certificate

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Assessments

15 assignments

Taught in English

There are 5 modules in this course

Health care professionals increasingly have to make clinical decisions in aging and diverse populations. Also, they have to deal with rising health care costs, fragmented health care supply and advancing medical technologies and IT systems. These developments go beyond every day practice and will require new skills. In this course we will walk you through key steps in designing a research study, from formulating the research question to common pitfalls you might encounter when interpreting your results. We will focus primarily on analytical studies used in etiological research, which aims to investigate the causal relationship between putative risk factors (or determinants) and a given disease or other outcome. However, the principles we will discuss hold true for most research questions, and you will also encounter these study designs in prognostic and diagnostic research settings.

This course is part of a Master's program Population Health Management at Leiden University (currently in development), which includes nine courses on Coursera (including this one). If you are interested in learning more about the Population Health Management approach follow the course "Population Health: Fundamentals of Population Health Management" on Coursera.

Welcome to Population Health: Study Design! In this module you will get to know what the scope is of this course and you will learn how to be successful at online studying.

What's included

2 videos3 readings1 discussion prompt1 plugin

2 videosβ€’Total 4 minutes
  • Population Health: Study Designβ€’2 minutes
  • How to succeed in your online class?β€’2 minutes
3 readingsβ€’Total 30 minutes
  • Meet the instructorsβ€’10 minutes
  • About this courseβ€’10 minutes
  • Glossaryβ€’10 minutes
1 discussion promptβ€’Total 10 minutes
  • Introduce yourselfβ€’10 minutes
1 pluginβ€’Total 2 minutes
  • Discover The World at Leiden University [video]β€’2 minutes

In this module you will start to formulate a research question. You will be introduced to the most important study designs in epidemiology, and work out which study design fits your specific research question.

What's included

9 videos2 readings4 assignments4 discussion prompts1 plugin

9 videosβ€’Total 49 minutes
  • Introductionβ€’1 minute
  • What is epidemiology?β€’4 minutes
  • How to create a good research question?β€’7 minutes
  • What is the research question?β€’5 minutes
  • Experimental versus observational studiesβ€’9 minutes
  • The cohort studyβ€’7 minutes
  • The case-control studyβ€’9 minutes
  • Bloodcurdling movies and measures of coagulation - a crossover trialβ€’7 minutes
  • To concludeβ€’1 minute
2 readingsβ€’Total 120 minutes
  • Observational research methods: cohort, cross sectional, and case-control studiesβ€’60 minutes
  • Designing a research project: randomised controlled trials and their principles.β€’60 minutes
4 assignmentsβ€’Total 210 minutes
  • Observational research methods: cohort, cross-sectional, and case-control studiesβ€’10 minutes
  • Designing a research project: randomised controlled trials and their principles.β€’10 minutes
  • Reflect on your goalsβ€’10 minutes
  • Test your knowledgeβ€’180 minutes
4 discussion promptsβ€’Total 120 minutes
  • How does epidemiology link to population health?β€’15 minutes
  • What is the research question?β€’15 minutes
  • Formulate three research questionsβ€’45 minutes
  • Which study design fits your research question?β€’45 minutes
1 pluginβ€’Total 20 minutes
  • Balance through randomisationβ€’20 minutes

In this module you will calculate frequency and effect measures, and apply them to your own research questions. In addition, you will practice with constructing a life table and drawing a Kaplan-Meier curve.

What's included

7 videos2 readings4 assignments1 discussion prompt1 plugin

7 videosβ€’Total 42 minutes
  • Introductionβ€’1 minute
  • Frequency measuresβ€’9 minutes
  • Effect measuresβ€’8 minutes
  • Odds and odds ratioβ€’6 minutes
  • Kaplan-Meierβ€’8 minutes
  • Thoughts on absolute versus relative riskβ€’8 minutes
  • To concludeβ€’1 minute
2 readingsβ€’Total 180 minutes
  • R tutorialβ€’120 minutes
  • Time partitionβ€’60 minutes
4 assignmentsβ€’Total 55 minutes
  • Calculate frequency and effect measuresβ€’20 minutes
  • Exposure windowβ€’5 minutes
  • Reflect on your goalsβ€’10 minutes
  • Test your knowledgeβ€’20 minutes
1 discussion promptβ€’Total 30 minutes
  • Frequency and effect measures in your study designβ€’30 minutes
1 pluginβ€’Total 45 minutes
  • Life table and Kaplan-Meierβ€’45 minutes

In this module different types of error will be discussed, which can be either random or systematic in nature. Subsequently, you will learn to recognize bias and confounding. You will additionally gain hands-on experience with standardisation.

What's included

7 videos1 reading3 assignments2 discussion prompts1 plugin

7 videosβ€’Total 41 minutes
  • Introductionβ€’1 minute
  • Puzzles in Epidemiologyβ€’3 minutes
  • Random versus systematic errorβ€’10 minutes
  • Confounding and biasβ€’9 minutes
  • Countering confoundingβ€’9 minutes
  • Standardisationβ€’8 minutes
  • To concludeβ€’1 minute
1 readingβ€’Total 120 minutes
  • Dealing with Biasesβ€’120 minutes
3 assignmentsβ€’Total 45 minutes
  • Dealing with Biasesβ€’5 minutes
  • Reflect on your goalsβ€’10 minutes
  • Test your knowledgeβ€’30 minutes
2 discussion promptsβ€’Total 180 minutes
  • Recognising potential biases and confoundersβ€’90 minutes
  • Study design - what can go wrong?β€’90 minutes
1 pluginβ€’Total 45 minutes
  • Balance through randomisationβ€’45 minutes

In this module you will calculate with averages, learn basic principles of causal inference, and be introduced to the concepts of regression to the mean and intention to treat.

What's included

6 videos2 readings4 assignments2 discussion prompts2 plugins

6 videosβ€’Total 26 minutes
  • Introductionβ€’1 minute
  • When do we know something is true?β€’8 minutes
  • Intention to treatβ€’7 minutes
  • Regression to the meanβ€’7 minutes
  • To concludeβ€’2 minutes
  • Course conclusionβ€’1 minute
2 readingsβ€’Total 110 minutes
  • Measurement scales and their summary statisticsβ€’20 minutes
  • Causation and causal inference in epidemiologyβ€’90 minutes
4 assignmentsβ€’Total 140 minutes
  • Final Assessmentβ€’90 minutes
  • Causation and causal inference in epidemiologyβ€’10 minutes
  • Reflect on your goalsβ€’10 minutes
  • Test your knowledgeβ€’30 minutes
2 discussion promptsβ€’Total 60 minutes
  • "Fake news"β€’45 minutes
  • Share your Glossaryβ€’15 minutes
2 pluginsβ€’Total 120 minutes
  • An exercise in datatypes and averagesβ€’60 minutes
  • Calculate posteriorsβ€’60 minutes

Instructors

Instructor ratings
4.0 (7 ratings)
Universiteit Leiden
1 Courseβ€’5,301 learners
Universiteit Leiden
1 Courseβ€’5,301 learners

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