Precision Medicine
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Precision Medicine
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Skills you'll gain
- Data Ethics
- General Medicine
- Bioinformatics
- Medical Science and Research
- Primary Care
- Oncology
- Health Informatics
- Precision Medicine
- Clinical Research
- Pharmacotherapy
- Pharmaceuticals
- Diagnostic Tests
- Pharmacology
- Biotechnology
- Healthcare Ethics
- Clinical Research Ethics
- Patient Education And Counseling
- Biomedical Technology
- Molecular Biology
- Health Policy
Details to know
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There are 6 modules in this course
This course will provide you with the key knowledge and tools to understand the fundamentals and practical implications of precision medicine, its opportunities and challenges. It will address precision-medicine era diagnostics, treatment selection, genetic counseling, public health interventions, and biomedical research. It will also deal with data science and ethical issues.
From genomic analysis and genetic counseling to cancer biomarkers, from risk assessment of chronic diseases to the understanding of gene-environment interactions, from pharmacogenomics to multi-omics data integration, experts will walk you through the many aspects of precision medicine, from the bench to the bedside and to population health. Designed for students with a bachelor-level training in life sciences, this course will also be useful for professionals who are increasingly expected to deal with precision medicine, including primary care physicians and other first-line healthcare professionals, cancer and non-communicable diseases specialists, public health policy and decision makers, as well as biomedical researchers and drug developers. Experts from the multiple domains of genetics and genomics, oncology, pharmacology, data sciences, ethics, and biomedical research will provide you with a comprehensive, multi-faceted overview of precision medicine, richly illustrated with practical examples and clinical case studies, and peppered with formative evaluations. Whether you are interested or intrigued by topics such as “genethics”, the analysis of exome sequencing, precision diabetes management, hereditary cancers, the ongoing revolution of genetic technologies, genome-exposome interactions, the pharmacogenetics of opioids, data deidentification, blockchain-base patient-consent documentation, or proteomics and biomarkers, this course will explain the concepts, offer insights and present concrete examples, thus providing you with an overall understanding of the rapidly evolving field of precision medicine. - update - The contents of this course have been updated and important corrections have been implemented thanks to learners' feedback. Many thanks to them!
What's included
12 videos5 readings6 assignments
12 videos•Total 55 minutes
- Trailer•2 minutes
- Welcome to the course•3 minutes
- Introduction to the module•3 minutes
- Human genome variabilty and phenotype consequences 1•1 minute
- Human genome variability and phenotype consequences 2•4 minutes
- Medical consultation (part 1)•9 minutes
- Exome sequencing analysis•9 minutes
- What are the options? discussion between the physician and the biologist•5 minutes
- Medical consultation (part 2)•3 minutes
- Rare genetic disorder and precision medicine•8 minutes
- Ethical, Legal and Social Implications (ELSI)•6 minutes
- Conclusion•2 minutes
5 readings•Total 50 minutes
- 📢 Important preliminary information: Evaluations and subtitles•10 minutes
- Syllabus•10 minutes
- List of Teachers•10 minutes
- Bibliographic References•10 minutes
- 📢 Important preliminary information: Evaluations and subtitles•10 minutes
6 assignments•Total 172 minutes
- Human genome variability and phenotype consequences•30 minutes
- Medical consultation part 1•30 minutes
- Exome sequencing analysis•30 minutes
- Rare genetic disorder and precision medicine•30 minutes
- Ethical, Legal and Social Implications (ELSI)•30 minutes
- Monogenic disease•22 minutes
What's included
10 videos5 assignments2 discussion prompts
10 videos•Total 43 minutes
- Introduction•2 minutes
- Genetics of complex disorders•7 minutes
- Environmental determinant•7 minutes
- Diabetes management today•3 minutes
- Diabetes risk assessment part 1•10 minutes
- The key points - answers to the discussion by the expert (part 1)•3 minutes
- Precision approaches in diabetes•1 minute
- Diabetes risk assessment (part 2)•6 minutes
- The key points - answers to the discussion by the expert (part 2)•3 minutes
- Conclusion•2 minutes
5 assignments•Total 140 minutes
- Genetics of complex disorders•30 minutes
- Environmental determinants•30 minutes
- How to evaluate the disease risk (part 1)•30 minutes
- How to evaluate the disease risk (part 2)•30 minutes
- Complex disease•20 minutes
2 discussion prompts•Total 20 minutes
- Diabetes management today•10 minutes
- Precision approches in diabetes•10 minutes
What's included
18 videos1 reading17 assignments
18 videos•Total 116 minutes
- Somatic mutation theory of cancer•5 minutes
- Synthetic lethality and oncogene addiction•5 minutes
- Clinically-orientated analysis•7 minutes
- Introduction to clinical ethics•9 minutes
- Objectives of precision oncology•4 minutes
- Tumor classification•4 minutes
- What is a biomarker?•7 minutes
- Somatic bioinformatics pipelines•10 minutes
- Molecular tumor board•6 minutes
- Ethical and societal implications•10 minutes
- Sporadic, familial and hereditary cancer•5 minutes
- Family history in oncology•5 minutes
- Genetic counselling in oncology•10 minutes
- Main hereditary cancer syndromes•9 minutes
- Case study 1 - part 1•5 minutes
- Case study 1 - part 2•7 minutes
- Case study 2 - part 1•5 minutes
- Case study 2 - part 2•4 minutes
1 reading•Total 10 minutes
- Further reading•10 minutes
17 assignments•Total 68 minutes
- Sommatic mutation theory of cancer•0 minutes
- Synthetic lethality and oncogene addiction•0 minutes
- Introduction to clinical ethics•0 minutes
- Objectives of precision oncology•0 minutes
- Tumor classification•0 minutes
- What is a biomarker?•0 minutes
- Somatic bioinformatics pipeline•30 minutes
- Molecular tumor board•0 minutes
- Ethical and societal implications•0 minutes
- Sporadic, familial and hereditary cancer•0 minutes
- Family history in oncology•0 minutes
- Genetic counselling in oncology•0 minutes
- Main hereditary cancer syndromes•2 minutes
- Case Study 1 - part 1•0 minutes
- Case Study 1 - part 2•0 minutes
- Case Study 2 - part 1•0 minutes
- Cancer•36 minutes
What's included
13 videos1 reading7 assignments
13 videos•Total 66 minutes
- Introduction to the module•1 minute
- The Revolution of Genetic Technologies•8 minutes
- Main Opportunities of Genomics•1 minute
- Genomics and Complex Chronic Diseases•9 minutes
- The Revolution of Environmental Technologies•8 minutes
- Genome-Exposome Interaction•2 minutes
- Big Data•7 minutes
- Validity and Massive Information•4 minutes
- Restitution, Unintended Findings and Actionable Variants•3 minutes
- Patients' Willingness to Discuss their Genomic Information•2 minutes
- Evidence-Based Precision Medicine•3 minutes
- Conclusion•2 minutes
- New Technologies and Personalized Health: Opportunities and Challenges•16 minutes
1 reading•Total 10 minutes
- Tyrell and all.•10 minutes
7 assignments•Total 142 minutes
- Testing the opportunities discussed•0 minutes
- Testing the illustration discussed•30 minutes
- Testing the concept of behaviome•0 minutes
- Testing the understanding of the Tyrell and all. results•30 minutes
- Big Data•30 minutes
- Testing challenges of translating genomics into clinical care•30 minutes
- Health and prevention•22 minutes
What's included
17 videos4 readings16 assignments
17 videos•Total 107 minutes
- Introduction to the module•2 minutes
- Variability in drug response•4 minutes
- Drug metabolism•7 minutes
- Role of Transporters in Drug Disposition•6 minutes
- Case - Pharmacogenomics of Statins•8 minutes
- Other Cardiovascular Case Studies•7 minutes
- Pharmacogenomics of opioids•7 minutes
- Tools for clinicians and patients•4 minutes
- Current Methods to Identify Pharmacogenomics Variants•7 minutes
- Phenotyping in the lab•6 minutes
- Drug development 1•9 minutes
- Drug development 2•9 minutes
- Pharmacovigilance•9 minutes
- Pharmacoeconomics of pharmacogenomics•6 minutes
- Citizen Centered Consent•8 minutes
- Data deidentification•5 minutes
- Conclusion and Future Perspectives•2 minutes
4 readings•Total 40 minutes
- Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism•10 minutes
- Table of Pharmacogenetic Associations•10 minutes
- Case study: antiaggregant and HIV•10 minutes
- Case Study: the example of oxycodone•10 minutes
16 assignments•Total 388 minutes
- Variability in drug response•30 minutes
- Drug metabolism•30 minutes
- Role of Transporters in Drug Disposition•30 minutes
- Pharmacogenomics of statins•30 minutes
- Other cardiovascular diseases•30 minutes
- Pharmacogenomics of opioids•30 minutes
- Tools of clinicians and patients•30 minutes
- Current Methods to Identify Pharmacogenomics Variants•30 minutes
- Phenotyping in the lab•30 minutes
- Drug development 1•30 minutes
- Drug development 2•30 minutes
- Pharmacovigilance•30 minutes
- Pharmacoeconomics and pharmacogenomics•0 minutes
- Citizen Centered Consent•0 minutes
- Data Deidentification•0 minutes
- Pharmacogenomics and Drug Development•28 minutes
What's included
10 videos2 readings8 assignments
10 videos•Total 59 minutes
- Introduction to the module•2 minutes
- First Steps of a Research Project•7 minutes
- Sample Collection, Biobanking and Data Generation/Recording•6 minutes
- Data Quality Control and Data Analysis•8 minutes
- Data dissemination, databases and publication•9 minutes
- Explanations by the expert•8 minutes
- Explanation by the expert: patient stratification in traumatic brain injury•7 minutes
- Explanations by the expert: Steroid Signatures in Toxicology•9 minutes
- Conclusion of the module•2 minutes
- Conclusion of the course in Precision Medicine•1 minute
2 readings•Total 20 minutes
- Estimating the causal tissues for complex traits and diseases•10 minutes
- Abstract section of the article•10 minutes
8 assignments•Total 204 minutes
- First steps of a research project•30 minutes
- Sample collection, biobanking and data generation/recording•30 minutes
- On Data videos above (2)•30 minutes
- Questions on published article•10 minutes
- Questions on abstract•30 minutes
- Patient stratification in traumatic brain injury•30 minutes
- Steroid signatures in toxicology•30 minutes
- Research•14 minutes
Instructors
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Reviewed on Jan 7, 2024
This is a high information rich domain of Medical practice. Learnt a lot of new technologies and approaches to disease management and treatment.
Reviewed on Jul 2, 2023
you deserve a 5 star. The course is so amazing and well explored by well composed instructors who used different methods to make the concept easy to grasp.
Reviewed on May 21, 2025
The course material and videos were very informative and helped me in developing new insights in the field
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