Statistical Analysis and Data Modeling in Healthcare
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Statistical Analysis and Data Modeling in Healthcare
This course is part of Introduction to Healthcare Data Analytics Specialization
Instructors: Ramesh Sannareddy
Included with
Recommended experience
Recommended experience
What you'll learn
Apply core statistical concepts, including descriptive and inferential statistics, to analyze and interpret healthcare data effectively.
Apply mathematical techniques to perform hypothesis testing, correlation analysis, and regression modeling in clinical and operational contexts.
Design and implement data models that support clinical decision-making, population health analysis, and healthcare operations.
Evaluate and validate statistical models using appropriate metrics to ensure accuracy, reliability, and ethical use of healthcare data.
Skills you'll gain
- Data Analysis
- Machine Learning Software
- Decision Tree Learning
- Clinical Data Management
- Healthcare Ethics
- Descriptive Analytics
- Data Literacy
- Statistical Machine Learning
- Machine Learning Methods
- Random Forest Algorithm
- Statistics
- Clinical Research
- Statistical Hypothesis Testing
- Regression Analysis
- Supervised Learning
- Data Analysis Software
- Statistical Analysis
- Health Informatics
- Analytics
- Predictive Analytics
Details to know
January 2026
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There are 4 modules in this course
Advance your career in healthcare data analytics by mastering the statistical and predictive modeling techniques used across clinical, operational, and population health settings.
In this hands-on course, you’ll learn how to analyze real-world healthcare datasets using descriptive statistics, hypothesis testing, regression analysis, and machine learning. Through interactive labs using Python and Jupyter Notebook in a Google Colab environment, you’ll compute key metrics, evaluate clinical groups, build predictive models, and interpret results with confidence. Designed for healthcare professionals, data analysts, and IT specialists, this course focuses on practical, industry-relevant skills. You’ll discover how to assess treatment effectiveness, explore associations among clinical variables, and generate predictions that support evidence-based clinical decision-making. The course also emphasizes ethical data practices, model validation, fairness, and the unique challenges of working with healthcare data. By the end of the course, you will be able to perform end-to-end healthcare data analysis, from data exploration and statistical testing to predictive modeling and interpretation. You’ll develop job-ready skills in healthcare analytics, statistical modeling, clinical data interpretation, and machine learning for healthcare, preparing you for roles such as healthcare data analyst, clinical data manager, or quality improvement specialist.
This module introduces you to the foundational concepts of descriptive statistics and their role in understanding healthcare data. You will explore how measures of central tendency, variability, and distribution shape provide meaningful summaries of patient populations, clinical characteristics, and health outcomes. Through guided examples drawn from real-world healthcare settings, you will see how descriptive statistics inform clinical decision-making, support quality improvement efforts, and highlight trends relevant to population health. By the end of the module, you will be able to compute, interpret, and clearly communicate key descriptive statistics, enabling you to identify important patterns, compare clinical groups, and generate insights from healthcare datasets with confidence.
What's included
8 videos5 readings4 assignments1 discussion prompt4 plugins
8 videos•Total 35 minutes
- Course Introduction•4 minutes
- Specialization Overview•5 minutes
- Meet Your Instructor•6 minutes
- Measures of Central Tendency•4 minutes
- Selecting the Right Measure of Center•4 minutes
- Variability in Clinical Measurements•5 minutes
- Common Distribution Types in Healthcare•4 minutes
- Impact of Data Distribution on Clinical Decisions•4 minutes
5 readings•Total 27 minutes
- Course Overview•2 minutes
- How to Make the Most of This Course•10 minutes
- Know your SME•3 minutes
- Lab: Analyzing Patient Vital Signs with Descriptive Statistics•10 minutes
- Module Summary: Descriptive Statistics in Healthcare•2 minutes
4 assignments•Total 39 minutes
- Graded Quiz: Descriptive Statistics in Healthcare •21 minutes
- Practice Quiz: Measuring Central Tendency in Clinical Data •6 minutes
- Practice Quiz: Measuring Variability and Dispersion in Patient Data•6 minutes
- Practice Quiz: Understanding Distributions in Clinical Datasets •6 minutes
1 discussion prompt•Total 2 minutes
- Your Day in One Number•2 minutes
4 plugins•Total 38 minutes
- Activity: How Ready Are You?•15 minutes
- Reading: Clinical Implications of Variability and Homogeneity•4 minutes
- Activity: Reveal the Hidden Story in Patient Data•15 minutes
- Reading: Integrating Descriptive Statistics for Healthcare Decision-Making•4 minutes
This module introduces learners to the foundations of hypothesis testing in a clinical analytics context. They will learn how to formulate statistical hypotheses, interpret p-values and confidence intervals, and understand the role of error rates and statistical power. Building on these fundamentals, the module explores widely used hypothesis tests for comparing clinical groups, including t-tests, ANOVA, and common nonparametric alternatives. Learners also study association tests for categorical data and correlation analysis for continuous variables. Through practical clinical examples such as treatment comparisons, disease prevalence analysis, and variable relationships, this module equips learners with the statistical tools needed to assess whether observed differences or patterns in healthcare data are meaningful and reliable.
What's included
6 videos3 readings4 assignments1 discussion prompt5 plugins
6 videos•Total 28 minutes
- Null and Alternative Hypotheses in Clinical Research •4 minutes
- P-Values and Confidence Intervals in Clinical Decisions •6 minutes
- T-Tests and ANOVA for Healthcare Outcomes•5 minutes
- Nonparametric Tests for Skewed Clinical Data •5 minutes
- Chi-Square Tests for Categorical Clinical Variables•4 minutes
- Correlation Analysis in Healthcare •4 minutes
3 readings•Total 22 minutes
- Lab: Evaluating Treatment Effectiveness with Hypothesis Testing•10 minutes
- Lab: Comparing Multiple Clinical Groups with ANOVA•10 minutes
- Module Summary: Hypothesis Testing for Clinical Data •2 minutes
4 assignments•Total 39 minutes
- Graded Quiz: Hypothesis Testing for Clinical Data •21 minutes
- Practice Quiz: Foundations of Hypothesis Testing•6 minutes
- Practice Quiz: Comparing Clinical Groups•6 minutes
- Practice Quiz: Clinical Associations and Relationships•6 minutes
1 discussion prompt•Total 2 minutes
- Reflecting on Treatment Comparison and Decision-Making•2 minutes
5 plugins•Total 42 minutes
- Reading: Key Concepts of Clinical Hypothesis Testing •4 minutes
- Activity: From Question to Evidence in Clinical Analytics•15 minutes
- Reading: Comparing Parametric and Nonparametric Methods •4 minutes
- Activity: Choosing the Right Test for Clinical Comparisons•15 minutes
- Reading: Association Tests in Healthcare Research •4 minutes
This module introduces learners to foundational regression and predictive modeling techniques widely used in healthcare analytics. Learners will begin with linear regression to analyze continuous clinical outcomes such as hospital length of stay, lab values, and healthcare costs. They then learn logistic regression to model binary clinical events and interpret key evaluation metrics such as odds ratios and ROC curves. Building on these fundamentals, the module explores core principles of machine learning and supervised modeling, including decision trees, ensemble methods, and performance validation. Learners also examine issues of model fairness, overfitting, and deployment challenges unique to healthcare. By the end of the module, they will be able to build, evaluate, and interpret predictive models that support clinical and operational decision-making.
What's included
5 videos3 readings4 assignments1 discussion prompt3 plugins
5 videos•Total 23 minutes
- Linear Regression for Clinical Metrics•5 minutes
- Model Diagnostics and Assumption Checking •4 minutes
- Logistic Regression for Binary Clinical Outcomes•5 minutes
- Supervised Learning Methods for Healthcare•5 minutes
- Model Validation, Bias, and Deployment Challenges •5 minutes
3 readings•Total 22 minutes
- Lab: Predicting Readmission Risk with Logistic Regression•10 minutes
- Lab: Building Predictive Models with Decision Trees and Random Forests•10 minutes
- Module Summary: Regression Analysis and Predictive Modeling•2 minutes
4 assignments•Total 39 minutes
- Graded Quiz: Regression Analysis and Predictive Modeling•21 minutes
- Practice Quiz: Linear Regression in Healthcare•6 minutes
- Practice Quiz: Logistic Regression for Clinical Classification•6 minutes
- Practice Quiz: Introduction to Predictive Modeling and ML Fundamentals•6 minutes
1 discussion prompt•Total 2 minutes
- Your Key Insight from Logistic Regression•2 minutes
3 plugins•Total 23 minutes
- Reading: Odds Ratios and ROC Metrics for Clinical Models•4 minutes
- Activity: Predicting Clinical Risk: From Logistic Regression to Model Evaluation•15 minutes
- Reading: Fundamentals of Machine Learning in Healthcare Analytics•4 minutes
In this capstone module, learners apply the full set of skills developed throughout the course to conduct an end-to-end analysis of a healthcare dataset. Students will clean and prepare data, compute descriptive statistics, perform hypothesis testing, and build regression and machine learning models to generate actionable clinical insights. The final project emphasizes not only technical accuracy but also clinical interpretation, communication, and ethical considerations. By completing this module, learners demonstrate their ability to independently analyze real-world healthcare data and produce evidence-based recommendations.
What's included
1 video2 readings1 assignment1 peer review1 discussion prompt2 plugins
1 video•Total 4 minutes
- Course Summary•4 minutes
2 readings•Total 3 minutes
- Congratulations and Next Steps•2 minutes
- Team and Acknowledgments•1 minute
1 assignment•Total 30 minutes
- Final Exam: Statistical Analysis and Data Modeling in Healthcare•30 minutes
1 peer review•Total 75 minutes
- Project: Emergency Department Analytics: From Statistics to Predictive Models•75 minutes
1 discussion prompt•Total 3 minutes
- Comparing Your Work •3 minutes
2 plugins•Total 11 minutes
- Reading: Final Project Overview•4 minutes
- Course Glossary: Statistical Analysis and Data Modeling in Healthcare•7 minutes
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Frequently asked questions
Yes. Throughout the course, you’ll work with realistic, de-identified clinical and administrative datasets. In each module, you’ll compute descriptive statistics, run hypothesis tests, and build regression and machine learning models using real-world healthcare scenarios.
Basic familiarity with spreadsheets and simple statistics is recommended, but advanced coding skills are not required. All labs are guided step-by-step in Jupyter Notebook (Google Colab), and starter code is provided to support learners new to Python-based analysis.
You’ll learn core analytical techniques used in healthcare, including descriptive statistics, hypothesis testing (t-tests, ANOVA, and chi-square), correlation analysis, linear regression, logistic regression, and introductory machine learning methods such as decision trees and random forests. You’ll also practice model validation and interpretation.
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