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metaphase

American  
[met-uh-feyz] / ˈmɛt əˌfeɪz /

noun

Cell Biology.
  1. the stage in mitosis or meiosis in which the duplicated chromosomes line up along the equatorial plate of the spindle.


metaphase British  
/ ˈmɛtəˌfeɪz /

noun

  1. biology the second stage of mitosis during which the condensed chromosomes attach to the centre of the spindle See also prophase anaphase telophase

  2. the corresponding stage of the first division of meiosis

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

metaphase Scientific  
/ mĕtə-fāz′ /
  1. The stage of cell division in which the duplicated chromosomes become aligned along the center of the cell, called the equatorial plate or metaphase plate. Metaphase lasts up to an hour, and ends in mitosis and the second division of meiosis when separation of the paired chromosomal strands (called chromatids) begins. In the first division of meiosis, the paired chromosomes separate from one another. Metaphase is preceded by prophase and followed by anaphase.

  2. See more at meiosis mitosis


Etymology

Origin of metaphase

First recorded in 1885–90; meta- + phase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

For almost twenty years, textbooks described CENP-E as a motor that pulled chromosomes to the metaphase plate.

From Science Daily • Dec. 10, 2025

The meiotic division is arrested in metaphase II. Fertilization triggers completion of the second meiotic division and the result is one ovum and an additional polar body.

From Textbooks • Jan. 1, 2015

Cell division is again arrested, this time at metaphase II. At ovulation, this secondary oocyte is released and travels toward the uterus through the oviduct.

From Textbooks • Apr. 25, 2013

Mitosis consists of five stages: prophase, prometaphase, metaphase, anaphase, and telophase.

From Textbooks • Apr. 25, 2013

Figure 4 shows the 52 chromosomes of a spermatogonial division in metaphase.

From Studies in Spermatogenesis Part I by Stevens, Nettie Maria

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.