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⇱ STERILE Definition & Meaning | Dictionary.com


sterile

American  
[ster-il, -ahyl] / ˈstɛr ɪl, -aɪl /

adjective

  1. free from living germs or microorganisms; aseptic.

    Successful operations rely on timely delivery of the sterile surgical instruments needed for each procedure.

  2. incapable of producing offspring; not producing offspring.

    Synonyms:
    unfruitful, infecund
    Antonyms:
    fertile
  3. barren; not producing vegetation.

    Attempts to cultivate the land have failed because of the sterile soil.

    Antonyms:
    fertile
  4. Botany.

    1. noting a plant in which reproductive structures fail to develop.

    2. bearing no stamens or pistils.

  5. not productive of results, ideas, etc.; fruitless.

  6. lacking vitality, vibrancy, interest, etc..

    Art can transform an otherwise sterile office into a happy, inspiring, and comforting space.


sterile British  
/ ˈstɛraɪl, stɛˈrɪlɪtɪ /

adjective

  1. unable to produce offspring; infertile

  2. free from living, esp pathogenic, microorganisms; aseptic

  3. (of plants or their parts) not producing or bearing seeds, fruit, spores, stamens, or pistils

  4. lacking inspiration or vitality; fruitless

  5. economics (of gold) not being used to support credit creation or an increased money supply

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

sterile Scientific  
/ stĕrəl,stĕrīl′ /
  1. Not able to produce offspring, seeds, or fruit; unable to reproduce.

  2. Free from disease-causing microorganisms.


Other Word Forms

  • half-sterile adjective
  • nonsterile adjective
  • nonsterilely adverb
  • sterilely adverb
  • sterileness noun
  • sterility noun
  • unsterile adjective

Etymology

Origin of sterile

First recorded in 1545–55; from Latin sterilis “barren, unfruitful”

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Strict temperature controls and workers in protective suits ensure that medicines are handled under sterile conditions and in guaranteed cold chains.

From Barron's • Apr. 5, 2026

The active ingredients in the drugs would be manufactured at an FDA-registered facility subject to inspection, and compounders are overseen by state boards of pharmacies to ensure sterile conditions.

From Salon • Apr. 4, 2026

The ’70s were punk, the ’80s were wild, and the ’90s by comparison felt sterile and corporatized, like we were all J.Crew bots, quoting Friends and drinking Starbucks.

From The Wall Street Journal • Mar. 25, 2026

An estimated 50% of sterile medical devices in the U.S. are treated with ethylene oxide.

From Los Angeles Times • Mar. 19, 2026

Obinze opened the door and stood aside for the others to go ahead, into the sterile hallway, where they paused to get their bearings, to be sure which way to go towards the register office.

From "Americanah" by Chimamanda Ngozi Adichie

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.