Voozh

Entry

7471              CDS       T01001

Symbol

WNT1, BMND16, INT1, OI15

Name

(RefSeq) proto-oncogene Wnt-1 precursor

K03209

wingless-type MMTV integration site family, member 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04150

mTOR signaling pathway

hsa04310

Wnt signaling pathway

hsa04390

Hippo signaling pathway

hsa04519

Cadherin signaling

hsa04550

Signaling pathways regulating pluripotency of stem cells

hsa04916

Melanogenesis

hsa04934

Cushing syndrome

hsa05010

Alzheimer disease

hsa05022

Pathways of neurodegeneration - multiple diseases

hsa05165

Human papillomavirus infection

hsa05200

Pathways in cancer

hsa05205

Proteoglycans in cancer

hsa05207

Chemical carcinogenesis - receptor activation

hsa05217

Basal cell carcinoma

hsa05224

Breast cancer

hsa05225

Hepatocellular carcinoma

hsa05226

Gastric cancer

Network

nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181  Salmonella
nt06215  WNT signaling (cancer)
nt06217  HH signaling (cancer)
nt06227  Nuclear receptor signaling (cancer)
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06269  Basal cell carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
nt06505  WNT signaling

Element

N00010

Mutation-inactivated PTCH1 to Hedgehog signaling pathway

N00017

Mutation-activated SMO to Hedgehog signaling pathway

N00056

Wnt signaling pathway, Canonical pathway

N00059

FZD7-overexpression to Wnt signaling pathway

N00060

LRP6-overexpression to Wnt signaling pathway

N01363

P4/MPA to nuclear-initiated progesterone signaling pathway

N01442

Wnt signaling modulation, Wnt inhibitor

N01443

Wnt signaling modulation, Wnt acylation

Disease

H00506

Osteogenesis imperfecta

H01593

Osteoporosis

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    7471 (WNT1)
   04390 Hippo signaling pathway
    7471 (WNT1)
   04150 mTOR signaling pathway
    7471 (WNT1)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    7471 (WNT1)
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    7471 (WNT1)
09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    7471 (WNT1)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    7471 (WNT1)
   05205 Proteoglycans in cancer
    7471 (WNT1)
   05207 Chemical carcinogenesis - receptor activation
    7471 (WNT1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    7471 (WNT1)
   05226 Gastric cancer
    7471 (WNT1)
   05217 Basal cell carcinoma
    7471 (WNT1)
   05224 Breast cancer
    7471 (WNT1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7471 (WNT1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    7471 (WNT1)
   05022 Pathways of neurodegeneration - multiple diseases
    7471 (WNT1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    7471 (WNT1)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7471 (WNT1)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Heparin
  Morphogens
   7471 (WNT1)

SSDB

Motif

Pfam:

wnt

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Position

12:48978322..48982620

AA seq 370 aa
MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRG
CRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLF
GREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLR
AVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCT
YSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNC
THTRVLHECL

NT seq 1113 nt +upstreamnt +downstreamnt
atggggctctgggcgctgttgcctggctgggtttctgctacgctgctgctggcgctggcc
gctctgcccgcagccctggctgccaacagcagtggccgatggtggggtattgtgaacgta
gcctcctccacgaacctgcttacagactccaagagtctgcaactggtactcgagcccagt
ctgcagctgttgagccgcaaacagcggcgtctgatacgccaaaatccggggatcctgcac
agcgtgagtggggggctgcagagtgccgtgcgcgagtgcaagtggcagttccggaatcgc
cgctggaactgtcccactgctccagggccccacctcttcggcaagatcgtcaaccgaggc
tgtcgagaaacggcgtttatcttcgctatcacctccgccggggtcacccattcggtggcg
cgctcctgctcagaaggttccatcgaatcctgcacgtgtgactaccggcggcgcggcccc
gggggccccgactggcactgggggggctgcagcgacaacattgacttcggccgcctcttc
ggccgggagttcgtggactccggggagaaggggcgggacctgcgcttcctcatgaacctt
cacaacaacgaggcaggccgtacgaccgtattctccgagatgcgccaggagtgcaagtgc
cacgggatgtccggctcatgcacggtgcgcacgtgctggatgcggctgcccacgctgcgc
gccgtgggcgatgtgctgcgcgaccgcttcgacggcgcctcgcgcgtcctgtacggcaac
cgcggcagcaaccgcgcttcgcgggcggagctgctgcgcctggagccggaagacccggcc
cacaaaccgccctccccccacgacctcgtctacttcgagaaatcgcccaacttctgcacg
tacagcggacgcctgggcacagcaggcacggcagggcgcgcctgtaacagctcgtcgccc
gcgctggacggctgcgagctgctctgctgcggcaggggccaccgcacgcgcacgcagcgc
gtcaccgagcgctgcaactgcaccttccactggtgctgccacgtcagctgccgcaactgc
acgcacacgcgcgtactgcacgagtgtctgtga

All links

Disease (3) 
 OMIM (3) 
Gene (22) 
 RefGene (17) 
 NCBI-PROTEINID (1) 
 NCBI-Gene (1) 
 HGNC (1) 
 Ensembl (1) 
 OC (1) 
Protein sequence (3) 
 UniProt (1) 
 SWISS-PROT (1) 
 RefSeq(pep) (1) 
DNA sequence (7) 
 RefSeq(nuc) (1) 
 GenBank (3) 
 EMBL (3) 
Protein domain (1) 
 Pfam (1) 
All databases (36) 

Download RDF

DBGET integrated database retrieval system

URL: https://www.genome.jp/entry/hsa:7471

⇱ KEGG T01001: 7471