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URL: https://www.kegg.jp/entry/D06363

⇱ KEGG DRUG: Ziconotide

👁 KEGG
Entry
D06363                      Drug                                   
Name
Ziconotide (USAN/INN);
Prialt (TN)
Formula
C102H172N36O32S7
Exact mass
2637.0983
Mol weight
2639.15
Structure 👁 Image
Sequence
Cys Lys Gly Lys Gly Ala Lys Cys Ser Arg Leu Met Tyr Asp Cys Cys
Thr Gly Ser Cys Arg Ser Gly Lys Cys
(Disulfide bridge: 1-16, 8-20, 15-25)
  Type
Peptide
Class
Cardiovascular agent
 DG01575  Calcium channel blocker
  DG01572  Calcium channel N type blocker
Remark
ATC code: N02BG08
Chemical structure group: DG00832
Product (DG00832): D08686<US>
Efficacy
Analgesic, Anti-inflammatory, Neuroprotectant, Calcium channel blocker
Comment
omega-Conotoxin [CPD:C19906] analog
Treatment of and brain ischemia
Target
CACNA1B [HSA:774] [KO:K04849]
  Pathway
hsa04020  Calcium signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02B OTHER ANALGESICS AND ANTIPYRETICS
    N02BG Other analgesics and antipyretics
     N02BG08 Ziconotide
      D06363  Ziconotide (USAN/INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01575  Calcium channel blocker
   DG01572  Calcium channel N type blocker
    DG00832  Ziconotide
     D06363  Ziconotide
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1B
     D06363  Ziconotide (USAN/INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01575  Calcium channel blocker
   DG01572  Calcium channel N type blocker
    DG00832  Ziconotide
Other DBs
CAS: 107452-89-1
PubChem: 47208020
LinkDB

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