| Entry |
|
|---|
| Name |
Tagraxofusp (USAN/INN);
Tagraxofusp (genetical recombination) (JAN);
Tagraxofusp-erzs;
Elzonris (TN) |
|---|
| Product |
|
|---|
| Formula |
C2553H4026N692O798S16
|
|---|
| Exact mass |
57659.1258
|
|---|
| Mol weight |
57694.51
|
|---|
| Sequence |
MGADDVVDSS KSFVMENFSS YHGTKPGYVD SIQKGIQKPK SGTQGNYDDD WKGFYSTDNK
YDAAGYSVDN ENPLSGKAGG VVKVTYPGLT KVLALKVDNA ETIKKELGLS LTEPLMEQVG
TEEFIKRFGD GASRVVLSLP FAEGSSSVEY INNWEQAKAL SVELEINFET RGKRGQDAMY
EYMAQACAGN RVRRSVGSSL SCINLDWDVI RDKTKTKIES LKEHGPIKNK MSESPNKTVS
EEKAKQYLEE FHQTALEHPE LSELKTVTGT NPVFAGANYA AWAVNVAQVI DSETADNLEK
TTAALSILPG IGSVMGIADG AVHHNTEEIV AQSIALSSLM VAQAIPLVGE LVDIGFAAYN
FVESIINLFQ VVHNSYNRPA YSPGHKTRPH MAPMTQTTSL KTSWVNCSNM IDEIITHLKQ
PPLPLLDFNN LNGEDQDILM ENNLRRPNLE AFNRAVKSLQ NASAIESILK NLLPCLPLAT
AAPTRHPIHI KDGDWNEFRR KLTFYLKTLE NAQAQQTTLS LAIF
(Disulfide bridge: 187-202, 407-475) |
|---|
| Type |
Peptide |
|---|
| Remark |
| Therapeutic category: | 4291 |
|
|---|
| Efficacy |
Antineoplastic, Immunotoxin |
|---|
| Comment |
Fusion protein, diphteria toxin-interleukin 3
Treatment of blastic plasmacytoid dendritic cell neoplasm (CD123-directed)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XX Other antineoplastic agents
L01XX67 Tagraxofusp
D11358 Tagraxofusp (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Molecular Target Inhibitors
Anti-CD123 Antibodies
Tagraxofusp
D11358 Tagraxofusp (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
429 Miscellaneous
4291 Other Antitumors
D11358 Tagraxofusp (USAN/INN); Tagraxofusp (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
Signaling molecules and receptors
Cytokine receptors
Interleukin receptors
IL3RA (CD123)
D11358 Tagraxofusp (USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D11358
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D11358
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D11358
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D11358
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| Other DBs |
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| LinkDB |
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