Wearables have the potential to address one of medicine’s major blind spots: the under-representation of women. They could help to close this gap by advancing measurement and monitoring into clinically meaningful insights of personalized data. However, realizing this potential requires validation, equity and clinical rigour to avoid reinforcing existing inequities.

Adolescents with chronic conditions face complex challenges during transition to adult care that often result in adverse health outcomes. Global best practice standards exist, but their implementation varies. Urgent, collaborative action, such as establishing youth-centred structured transition programmes, is needed to ensure adolescents are empowered to manage their health and thrive.

Globally, pressure is increasing for healthcare systems to deliver on the promise of genomic medicine to improve patient well-being. Although primary care is the ideal setting for leading this effort, primary health systems are overburdened and ill-equipped for this task in many jurisdictions. Integrating professional genetic counsellors may be a solution.

As the pace of innovation accelerates and societies change, the needs of all patients must remain the focus of healthcare. At 10 years, Nature Reviews Disease Primers remains committed to providing accessible, authoritative knowledge to those who strive to improve the lives of individuals in need of care.