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Protein-coding gene in humans
CD109
Identifiers
AliasesCD109, CPAMD7, p180, r150, CD109 molecule
External IDsOMIM: 608859; MGI: 2445221; HomoloGene: 25183; GeneCards: CD109; OMA:CD109 - orthologs
Gene location (Human)
πŸ‘ Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Band6q13Start73,695,785 bp[1]
End73,828,316 bp[1]
Gene location (Mouse)
πŸ‘ Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Band9|9 E1Start78,522,828 bp[2]
End78,623,535 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tibia

  • skin of arm

  • skin of thigh

  • skin of hip

  • synovial membrane

  • vulva

  • tendon of biceps brachii

  • cartilage tissue

  • nipple

  • gums
Top expressed in
  • skin of external ear

  • calvaria

  • spermatid

  • body of femur

  • skin of back

  • ankle

  • cornea

  • endothelial cell of lymphatic vessel

  • lip

  • stroma of bone marrow
More reference expression data
BioGPS
πŸ‘ Image


πŸ‘ Image


πŸ‘ Image
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

135228

235505

Ensembl

ENSG00000156535

ENSMUSG00000046186

UniProt

Q6YHK3

Q8R422

RefSeq (mRNA)

NM_001159587
NM_001159588
NM_133493

NM_153098

RefSeq (protein)

NP_001153059
NP_001153060
NP_598000

NP_694738

Location (UCSC)Chr 6: 73.7 – 73.83 MbChr 9: 78.52 – 78.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CD109 (Cluster of Differentiation 109) is a human gene.[5]

CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system (HPA15),[6] implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990; Lin et al., 2002).[supplied by OMIM][5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000156535 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046186 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: CD109 CD109 molecule".
  6. ^ "IPD - HPA Sequence Database| EBI".

Further reading

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External links

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