Protein-coding gene in the species Homo sapiens
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 is a protein that in humans is encoded by the GNG11 gene.[5][6]
This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein.
As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas.[6]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000127920 ā Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032766 ā Ensembl, May 2017
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- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
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- ^ a b "Entrez Gene: GNG11 guanine nucleotide binding protein (G protein), gamma 11".
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- Ruiz-Ballesteros E, Mollejo M, Rodriguez A, et al. (2005). "Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis". Blood. 106 (5): 1831ā8. doi:10.1182/blood-2004-10-3898. PMID 15914563.
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- Hossain MN, Sakemura R, Fujii M, Ayusawa D (2007). "G-protein gamma subunit GNG11 strongly regulates cellular senescence". Biochem. Biophys. Res. Commun. 351 (3): 645ā50. doi:10.1016/j.bbrc.2006.10.112. PMID 17092487.
