f[n_, b_] := Block[{k = 10^(n + 1), p = Permutations[ Join[ Table[b, {i, 1, n}], {x}]], c = Complement[Table[j, {j, 0, 9}], {b}], q = {}}, Do[q = Append[q, Replace[p, x -> c[[i]], 2]], {i, 1, 9}]; r = Min[ Select[ FromDigits /@ Flatten[q, 1], PrimeQ[ # ] & ]]; If[r ? Infinity, r, p = Permutations[ Join[ Table[ b, {i, 1, n}], {x, y}]]; q = {}; Do[q = Append[q, Replace[p, {x -> c[[i]], y -> c[[j]]}, 2]], {i, 1, 9}, {j, 1, 9}]; Min[ Select[ FromDigits /@ Flatten[q, 1], PrimeQ[ # ] & ]]]]; Table[ f[n, 3], {n, 1, 18}]
Table[Sort[Flatten[Table[Select[FromDigits/@Permutations[Join[{n}, PadRight[{}, i, 3]]], PrimeQ], {n, 0, 9}]]][[1]], {i, 20}] (*
Harvey P. Dale, Feb 28 2015 *)