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URL: https://willitrunai.com/can-run/deepseek-r1-distill-32b-on-instinct-mi300a-128gb

⇱ DeepSeek R1 Distill 32B on AMD Instinct MI300A 128GB? YES

Can DeepSeek R1 Distill 32B run on AMD Instinct MI300A 128GB?

YES — Runs Great

A73Great
○Estimated from fit model

DeepSeek R1 Distill 32B needs ~37.1 GB VRAM. AMD Instinct MI300A 128GB has 128.0 GB. With Q4_K_M quantization, expect ~205 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
Share:

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 37.1 GB, 205.3 tok/s, Runs well
37.1 GB required128.0 GB available
29% VRAM used

Fit status

Runs well

Decode

205.3 tok/s

TTFT

943 ms

Safe context

33K

Memory

37.1 GB / 128.0 GB

Memory breakdown

Weights19.5 GB
KV Cache3.9 GB
Runtime0.9 GB
Headroom12.8 GB

See how fast it feels

See how fast it feelsDeepSeek R1 Distill 32B on AMD Instinct MI300A 128GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 205.3 tok/s decode · 943ms TTFT (warm) · 513 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatARuns well205.3 tok/s514 ms33K
CodingARuns well205.3 tok/s943 ms33K
Agentic CodingARuns well205.3 tok/s1372 ms33K
ReasoningARuns well205.3 tok/s1115 ms33K
RAGARuns well205.3 tok/s1715 ms33K

Quantization options

How DeepSeek R1 Distill 32B (32B params) fits at each quantization level on AMD Instinct MI300A 128GB (128.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
12.5 GB
LowB64
Q3_K_S
3
15.7 GB
LowB64
NVFP4
4
17.9 GB
MediumB64
Q4_K_M
4
19.5 GB
MediumB64
Q5_K_M
5
23.0 GB
HighB65
Q6_K
6
26.2 GB
HighB65
Q8_0
8
34.2 GB
Very HighB67
F16Best for your GPU
16
65.6 GB
MaximumA72

Get started

Copy-paste commands to run DeepSeek R1 Distill 32B on your machine.

Run

ollama run deepseek-r1:32b

Your hardware

More models your AMD Instinct MI300A 128GB can run

ModelParamsGradeDecodeCapabilities
👁 Mistral
Devstral 2 123B Instruct		123BS53.8 tok/s
👁 Alibaba
Qwen 3.5 122B A10B		122BS149.2 tok/s
👁 Alibaba
Qwen 3.6 35B A3B		35BS471.5 tok/s
👁 Alibaba
Qwen 3.5 35B A3B		35BS512.7 tok/s
👁 Mistral
Mistral Small 4 119B		119BS161.7 tok/s

Frequently asked questions

See all results for AMD Instinct MI300A 128GBSee all hardware for DeepSeek R1 Distill 32B