~$2,499 MSRP
Can Mistral Small 3.2 24B Instruct 2506 run on AMD Instinct MI60 32GB?
YES — Runs Great
Mistral Small 3.2 24B Instruct 2506 needs ~21.6 GB VRAM. AMD Instinct MI60 32GB has 32.0 GB. With Q4_K_M quantization, expect ~34 tok/s.
Operating mode
Choose the run profile you care about
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
Fit status
Runs well
Decode
34.3 tok/s
TTFT
5649 ms
Safe context
75K
Memory
21.6 GB / 32.0 GB
Memory breakdown
See how fast it feels
What limits this setup
This setup is broadly balanced for this model.
No major red flags
This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.
Best improvement path
Performance by workload
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | C | Runs well | 34.3 tok/s | 3081 ms | 75K |
| Coding | C | Runs well | 34.3 tok/s | 5649 ms | 75K |
| Agentic Coding | C | Runs well | 34.3 tok/s | 8216 ms | 75K |
| Reasoning | C | Runs well | 34.3 tok/s | 6676 ms | 75K |
| RAG | C | Runs well | 34.3 tok/s | 10270 ms | 75K |
Quantization options
How Mistral Small 3.2 24B Instruct 2506 (24B params) fits at each quantization level on AMD Instinct MI60 32GB (32.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 9.4 GB | Low | C46 |
Q3_K_S | 3 | 11.8 GB | Low | C47 |
NVFP4 | 4 | 13.4 GB | Medium | C48 |
Q4_K_M | 4 | 14.6 GB | Medium | C48 |
Q5_K_M | 5 | 17.3 GB | High | C50 |
Q6_K | 6 | 19.7 GB | High | C49 |
Q8_0Best for your GPU | 8 | 25.7 GB | Very High | C49 |
F16 | 16 | 49.2 GB | Maximum | F0 |
Get started
Copy-paste commands to run Mistral Small 3.2 24B Instruct 2506 on your machine.
Run
lms load hf-unsloth--mistral-small-3-2-24b-instruct-2506-gguf && lms server startUpgrade options
Hardware that runs Mistral Small 3.2 24B Instruct 2506 well
Raises estimated decode speed by about 160%.
Adds memory headroom for longer context windows and future model growth.
~$10,000 MSRP
