Can Mistral Small 24B run on AMD Instinct MI60 32GB?

YES — Runs Great

S85Excellent

○Estimated from fit model

Mistral Small 24B needs ~21.2 GB VRAM. AMD Instinct MI60 32GB has 32.0 GB. With Q4_K_M quantization, expect ~37 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 21.2 GB, 36.8 tok/s, Runs well

21.2 GB required32.0 GB available

66% VRAM used

Fit status

Runs well

Decode

36.8 tok/s

TTFT

5255 ms

Safe context

33K

Memory

21.2 GB / 32.0 GB

Memory breakdown

Weights14.6 GB

KV Cache2.4 GB

Runtime0.9 GB

Headroom3.2 GB

See how fast it feels

See how fast it feelsMistral Small 24B on AMD Instinct MI60 32GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
 if len(arr) <= 1:
 return arr
 pivot = arr[len(arr) // 2]
 left = [x for x in arr if x < pivot]
 middle = [x for x in arr if x == pivot]
 right = [x for x in arr if x > pivot]
 return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
 """Sort a list using the quicksort algorithm.

 Args:
 arr: List of integers to sort.

 Returns:
 A new sorted list.
 """
 if len(arr) <= 1:
 return arr
 pivot = arr[len(arr) // 2]
 left = [x for x in arr if x < pivot]
 middle = [x for x in arr if x == pivot]
 right = [x for x in arr if x > pivot]
 return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 36.8 tok/s decode · 5.3s TTFT (warm) · 92 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	A	Runs well	36.8 tok/s	2866 ms	33K
Coding	S	Runs well	36.8 tok/s	5255 ms	33K
Agentic Coding	S	Runs well	36.8 tok/s	7643 ms	33K
Reasoning	S	Runs well	36.8 tok/s	6210 ms	33K
RAG	S	Runs well	36.8 tok/s	9554 ms	33K

Quantization options

How Mistral Small 24B (24B params) fits at each quantization level on AMD Instinct MI60 32GB (32.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	9.4 GB	Low	A78
Q3_K_S	3	11.8 GB	Low	A79
NVFP4	4	13.4 GB	Medium	A80
Q4_K_M	4	14.6 GB	Medium	A80
Q5_K_M	5	17.3 GB	High	A81
Q6_K	6	19.7 GB	High	A81
Q8_0Best for your GPU	8	25.7 GB	Very High	A80
F16	16	49.2 GB	Maximum	F0

Get started

Copy-paste commands to run Mistral Small 24B on your machine.

Run

ollama run mistral-small

Your hardware

More models your AMD Instinct MI60 32GB can run

Model	Params	Grade	Decode
👁 Alibaba Qwen3-Coder 30B A3B Instruct	30.5B	S	75.9 tok/s
👁 Alibaba Qwen 3.5 27B	27B	S	32.9 tok/s
👁 Alibaba Qwen 3.6 27B	27B	S	20.5 tok/s
👁 Alibaba Qwen 3.6 35B A3B	35B	S	63.8 tok/s
👁 Alibaba Qwen3-VL 30B A3B Instruct	30B	S	78.5 tok/s

Frequently asked questions

See all results for AMD Instinct MI60 32GB See all hardware for Mistral Small 24B

URL: https://willitrunai.com/can-run/mistral-small-24b-on-instinct-mi60-32gb

⇱ Mistral Small 24B on AMD Instinct MI60 32GB? YES