VOOZH about

URL: https://willitrunai.com/can-run/nemotron-70b-on-instinct-mi300a-128gb

⇱ Nemotron 70B on AMD Instinct MI300A 128GB? YES

Can Nemotron 70B run on AMD Instinct MI300A 128GB?

YES — Runs Great

A74Great
○Estimated from fit model

Nemotron 70B needs ~61.3 GB VRAM. AMD Instinct MI300A 128GB has 128.0 GB. With Q4_K_M quantization, expect ~95 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
Share:

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 61.3 GB, 94.5 tok/s, Runs well
61.3 GB required128.0 GB available
48% VRAM used

Fit status

Runs well

Decode

94.5 tok/s

TTFT

2049 ms

Safe context

131K

Memory

61.3 GB / 128.0 GB

Memory breakdown

Weights42.7 GB
KV Cache4.9 GB
Runtime0.9 GB
Headroom12.8 GB

See how fast it feels

See how fast it feelsNemotron 70B on AMD Instinct MI300A 128GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 94.5 tok/s decode · 2.0s TTFT (warm) · 236 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatARuns well94.5 tok/s1118 ms131K
CodingARuns well94.5 tok/s2049 ms131K
Agentic CodingARuns well94.5 tok/s2980 ms131K
ReasoningARuns well94.5 tok/s2421 ms131K
RAGARuns well94.5 tok/s3725 ms131K

Quantization options

How Nemotron 70B (70B params) fits at each quantization level on AMD Instinct MI300A 128GB (128.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
27.3 GB
LowB62
Q3_K_S
3
34.3 GB
LowB63
NVFP4
4
39.2 GB
MediumB64
Q4_K_M
4
42.7 GB
MediumB65
Q5_K_M
5
50.4 GB
HighB66
Q6_K
6
57.4 GB
HighB67
Q8_0Best for your GPU
8
74.9 GB
Very HighB69
F16
16
143.5 GB
MaximumF0

Get started

Copy-paste commands to run Nemotron 70B on your machine.

Run

ollama run nemotron

Your hardware

More models your AMD Instinct MI300A 128GB can run

ModelParamsGradeDecodeCapabilities
👁 Mistral
Devstral 2 123B Instruct		123BS53.8 tok/s
👁 Alibaba
Qwen 3.5 122B A10B		122BS149.2 tok/s
👁 Mistral
Mistral Small 4 119B		119BS161.7 tok/s
👁 OpenAI
GPT-OSS 120B		117BS56.5 tok/s
👁 Cohere
Command A 111B		111BS59.8 tok/s

Frequently asked questions

See all results for AMD Instinct MI300A 128GBSee all hardware for Nemotron 70B