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AMD
Operating mode
Use this to bias workload recommendations toward responsiveness, background autonomy, lighter serving, or multi-GPU scale-out.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
The AMD Instinct MI300X 192GB is AMD's flagship CDNA 3 discrete GPU accelerator, targeting LLM inference and training at scale. With 192 GB of HBM3 memory and 5.3 TB/s of bandwidth, it outspecifies the NVIDIA H100 80GB in raw memory capacity and bandwidth. The 1307 TFLOPS FP16 compute, FP8 support, and full ROCm maturity make it AMD's primary datacenter AI product and the main alternative to NVIDIA in large-scale inference deployments.
Beyond LLMs
What AI tasks this GPU can handle — from text generation to image and video creation.
| Capability | Status | Representative Model | Detail |
|---|---|---|---|
| LLM Chat (7B) | Runs natively | Llama 3.1 8B Q4 | — |
| LLM Coding (30B) | Runs natively | Qwen 3 30B Q4 | — |
| LLM Large (70B) |
Architecture
CDNA 3 powers the Instinct MI300X (GPU-only, 192 GB HBM3) and MI300A (APU with integrated CPU). It features advanced packaging with up to 12 chiplets and native FP8 support for AI inference.
AI Relevance
The MI300X with 192 GB HBM3 can hold even the largest open-weight models (70B+ at full precision) entirely in GPU memory. FP8 support and mature ROCm stack make it a serious competitor to NVIDIA H100 for AI inference.
Chat
SQwen 3.5 122B A10B matches Chat and keeps a practical fit profile. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, lm-studio.
Coding
SDevstral 2 123B Instruct is a specialized fit for Coding. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, lm-studio.
Agentic Coding
Just out of reach
High-quality models that need a bit more memory
Image & Video Generation
52 of 52 models can generate images or video on your AMD Instinct MI300X 192GB
| Model | Max Resolution | Gen Time | Grade |
|---|---|---|---|
| SD TurboImage | 512×512 | 0ms | S |
| Stable Diffusion 1.5Image | 512×768 | 100ms | S |
| Realistic Vision v5.1Image | 512×768 | 100ms | S |
| DreamShaper 8Image | 512×768 | 100ms | S |
| LCM DreamShaper v7 |
Multi-GPU scaling
Scale out with multiple GPUs for larger models. Infinity Fabric provides 896 GB/s inter-GPU bandwidth with 12% overhead.
| Config | Effective memory | Models that fit | Est. bandwidth |
|---|---|---|---|
| 1× AMD | 192 GB | 359/374 | 5,300 GB/s |
| 2× AMD | 384 GB | 366/374 | 9,328 GB/s |
| 4× AMD | 768 GB | 373/374 | 18,656 GB/s |
| 8× AMD | 1536 GB | 374/374 | 37,312 GB/s |
Model counts use default quantization at coding workload settings. Multi-GPU scaling factor: 0.88× per additional GPU.
Upgrade paths
See what you unlock with more powerful hardware
Upgrade options
Unlocks 15 additional models that do not fit on the current setup.
Lifts average decode speed across fitting models by about 135%.
Infinity Fabric gives this scale-out path a cleaner inter-GPU story than PCIe-only builds.
~$15,000 MSRP
Unlocks 4 additional models that do not fit on the current setup.
~$20,000 MSRP
Unlocks 5 additional models that do not fit on the current setup.
Lifts average decode speed across fitting models by about 14%.
~$8,000 MSRP
Compare with similar
| Runs natively |
| Llama 3.1 70B Q4 |
| — |
| Image Gen (SDXL) | Runs natively | SDXL 1.0 FP16 | ~200ms per image |
| Image Gen (Flux) | Runs natively | Flux.1 Dev FP16 | ~~1.1s per image |
| Image Gen (SD 3.5) | Runs natively | SD 3.5 Large FP16 | ~~1.3s per image |
| Video Short (25f) | Runs natively | LTX Video 2B | ~200ms/frame |
| Video Long (100f) | Runs natively | Wan Video 14B | ~600ms/frame |
Devstral 2 123B Instruct is a specialized fit for Agentic Coding. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, lm-studio.
Reasoning
SDevstral 2 123B Instruct matches Reasoning and keeps a practical fit profile. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, lm-studio.
RAG
SQwen 3.5 122B A10B matches RAG and keeps a practical fit profile. It is a recent-generation family, which helps on current local SOTA workloads. It fits natively with comfortable headroom. Context coverage stays within the requested workload envelope. Known distribution channels: huggingface, lm-studio.
| 512×768 |
| 0ms |
| S |
| PixArt-SigmaImage | 1024×1024 | 200ms | S |
| FramePack I2VVideo | 1280×720 | 400ms/frame | S |
| SDXL TurboImage | 512×512 | 0ms | S |
| SDXL LightningImage | 1024×1024 | 100ms | S |
| Stable Diffusion XL 1.0Image | 1024×1024 | 200ms | S |
| Playground v2.5Image | 1024×1024 | 400ms | S |
| RealVisXL v5.0Image | 1024×1024 | 300ms | S |
| DreamShaper XLImage | 1024×1024 | 300ms | S |
| Juggernaut XL v9Image | 1024×1024 | 300ms | S |
| Animagine XL 3.1Image | 1024×1024 | 300ms | S |
| Pony Diffusion V6 XLImage | 1024×1024 | 300ms | S |
| Animagine XL 4.0Image | 1024×1024 | 300ms | S |
| Illustrious XLImage | 1024×1024 | 300ms | S |
| Wan Video 2.1 1.3BVideo | 480×832 | 200ms/frame | S |
| Stable Diffusion 3.5 MediumImage | 1024×1024 | 400ms | S |
| Flux.2 Klein 4BImage | 1024×1024 | 100ms | S |
| LTX Video 2BVideo | 1280×720 | 200ms/frame | S |
| KolorsImage | 1024×1024 | 500ms | S |
| Stable CascadeImage | 1024×1024 | 600ms | S |
| AuraFlow v0.3Image | 1536×1536 | ~1.1s | S |
| Stable Diffusion 3.5 LargeImage | 1024×1024 | ~1.3s | S |
| Stable Diffusion 3.5 Large TurboImage | 1024×1024 | 200ms | S |
| CogVideoX 2BVideo | 720×480 | 200ms/frame | S |
| HunyuanVideoVideo | 720×1280 | 400ms/frame | S |
| ChromaImage | 1024×1024 | 200ms | S |
| Z-Image TurboImage | 1536×1536 | 300ms | S |
| Flux.1 DevImage | 1024×1024 | ~1.1s | S |
| Flux.1 SchnellImage | 1024×1024 | 200ms | S |
| LTX Video 13BVideo | 1280×720 | 400ms/frame | S |
| Flux.1 Kontext DevImage | 1024×1024 | ~1.2s | S |
| AnimateDiff v1.5.3Video | 512×768 | 100ms/frame | S |
| Cosmos Diffusion 7BVideo | 1024×576 | 400ms/frame | S |
| CogVideoX 5BVideo | 720×480 | 300ms/frame | S |
| Wan2.2 TI2V 5BVideo | 832×480 | 300ms/frame | S |
| Flux.2 Klein 9BImage | 1024×1024 | 100ms | S |
| Flux.1 Fill DevImage | 1024×1024 | ~1s | S |
| Mochi 1 PreviewVideo | 848×480 | 400ms/frame | S |
| HunyuanVideo 1.5Video | 720×1280 | 400ms/frame | S |
| Helios 14BVideo | 1280×720 | 500ms/frame | S |
| SkyReels V2 14BVideo | 1280×720 | 500ms/frame | S |
| Wan Video 2.1 14BVideo | 720×1280 | 500ms/frame | S |
| Wan Video 2.2 14BVideo | 720×1280 | 500ms/frame | S |
| Qwen ImageImage | 1024×1024 | 400ms | S |
| Qwen Image EditImage | 1024×1024 | 400ms | S |
| Flux.2 DevImage | 1024×1024 | ~11.6s | S |
| MAGI-1Video | 1280×720 | 600ms/frame | S |
| HunyuanImage 3.0Image | 1024×1024 | 700ms | B |
Image models estimated at 1024×1024 (28 steps, FP16). Video models estimated at 768×512 (25 frames, 30 steps, FP16). Actual performance varies with runtime and system load.
Buying advice
Excellent choice for local AI
Runs 40 of 50 top models well — a strong all-rounder for local inference.
192.0 GB
VRAM
$15,000
MSRP
$78/GB
Cost per GB VRAM
Best models for this GPU
What will limit you first
This setup is broadly balanced for this model.
Very little memory headroom
You can run the model, but there is not much room left for longer context, bigger batches, extra apps, or future model updates.
Best upgrade itinerary
Buy headroom, not only minimum fit
A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.
Unlocks 4 additional models that do not fit on the current setup.
Want more headroom? AMD Instinct MI325X 256GB (256.0 GB VRAM) is the next step up.
