AMD EPYC 4345P 8-Core CPU Performance

Written by Michael Larabel in Processors on 9 June 2025 at 11:00 AM EDT. Page 4 of 8. 11 Comments.

👁 LAMMPS Molecular Dynamics Simulator benchmark with settings of Model: Rhodopsin Protein. EPYC 4585PX was the fastest.

The LAMMPS molecular dynamics simulator was one of the rare cases where there was a tie between the EPYC 4345P and Xeon 6369P... At least for raw performance while the Grado CPUs delivered better power efficiency and value.

👁 LAMMPS Molecular Dynamics Simulator benchmark with settings of Model: 20k Atoms. EPYC 4585PX was the fastest.

But for those dealing with larger molecular dynamics simulations, the EPYC 4345P cane out at 1.2x the performance of the Xeon 6369P.

👁 Graph500 benchmark with settings of Scale: 26. EPYC 4585PX was the fastest.

👁 RELION benchmark with settings of Test: Basic, Device: CPU. EPYC 4585PX was the fastest.

👁 High Performance Conjugate Gradient benchmark with settings of X Y Z: 144 144 144, RT: 60. Xeon 6369P was the fastest.

👁 NAMD benchmark with settings of Input: ATPase with 327,506 Atoms. EPYC 4585PX was the fastest.

👁 NAMD benchmark with settings of Input: STMV with 1,066,628 Atoms. EPYC 4585PX was the fastest.

👁 GROMACS benchmark with settings of Implementation: MPI CPU, Input: water_GMX50_bare. EPYC 4585PX was the fastest.

With the exception of HPCG, the EPYC 4004/4005 processors were dominating Intel's top-end Xeon 6300 series processor.

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URL: https://www.phoronix.com/review/amd-epyc-4345p/4

⇱ AMD EPYC 4345P 8-Core CPU Performance Review - Phoronix

AMD EPYC 4345P 8-Core CPU Performance