AI Compatibility Tier List

AMD Instinct MI250 128GB

374 AI models ranked by how well they run on your 128 GB VRAM hardware. Best match: Qwen 3.5 122B A10B (score: 99).

Tier Distribution

S Tier -- Perfect Fit (28 models)

These models run flawlessly with headroom to spare.

A Tier -- Great Fit (54 models)

Excellent performance with comfortable memory margins.

B Tier -- Good Fit (60 models)

Solid performance, may need quantization or reduced context.

C Tier -- Tight Fit (188 models)

Runs with offloading or significant compromises.

F Tier -- Can't Run (44 models)

Too heavy for this hardware.